PubMed Health⌕ Search

Biomedical subjects

A K Ott

Publications and source records attributed to A K Ott.

8 recordsLinked to original sources

An immunodominant antigen of Candida albicans shows homology to the enzyme enolase.

Antibody to an immunodominant antigen of approximately 48 kDa is found in a high proportion of patients with mucocutaneous or systemic infections of the yeast Candida albicans. A cDNA encoding part of the 48 kDa antigen has been isolated. From the deduced amino acid sequence of the cDNA clone, the 48 kDa antigen shows homology to the enzyme enolase.

Acquired Immunodeficiency Syndrome↗

Autoimmunity as a factor in recurrent vaginal candidosis and the minor vestibular gland syndrome.

Chronic vaginal candidosis is a significant cause of morbidity in women, but its causes are not yet understood. We propose that in genetically susceptible women a candidal infection elicits responses that cross-react with self-antigens. Control of these deleterious responses may compromise the normal mechanisms of resistance and predispose to recurrent infection. Furthermore, the local inflammation caused by these autoreactive cells may contribute to other forms of vaginitis.

Animals↗

Modern perspectives on vaginal candidiasis.

Vaginal thrush is not only a medical problem--it also causes significant psychological and emotional distress, particularly if the infections persist or recur. Women who suffer from frequent recurrences often express dissatisfaction with the treatment they receive, and such comments may be provoked by a lack of awareness on the part of the physician of the natural history of the infection, and of the difficulties inherent in its diagnosis and treatment.

Candidiasis, Vulvovaginal↗

Tungiasis: imported disease.

A case of importation of the sandflea Tunga penetrans is reported. If this species were to become established in Australia, there could be medical and socioeconomic repercussions.

Adult↗

Prenatal screening for markers of hepatitis B in aboriginal mothers resident in non-metropolitan Western Australia.

Of 1947 Aboriginal women who resided in non-metropolitan regions of Western Australia and gave birth during January 1983 to February 1985, 42% of women were screened prenatally for the presence of hepatitis B surface antigen (HBsAg). The proportions of Aboriginal women who were screened varied from 17% in the southern divisions to 72% in the Kimberley region. The screening programme identified 29 Aboriginal women with a positive result of the test. On this basis, the estimated prevalence of HBsAg among non-metropolitan Aboriginal women was 3.6% (95% confidence interval, 2.5%-5.1%). According to the geographical location of the mother's residence, the observed prevalence of HBsAg varied from 0 in the southern divisions to around 4%-5% in the central and eastern divisions.

Carrier State↗