Biomedical subjects

A Kadrmas

Publications and source records attributed to A Kadrmas.

4 recordsLinked to original sources

PubMed1986

Genetic approach to heterogeneity in psychoses: relationship of a family history of mania or depression to course in bipolar illness.

A specific family history or genetic background may be used to distinguish valid subgroups in patients who show similar symptoms. Also, a familial background may predict differences in other characteristics, i.e. course of illness, response to treatment or biological characteristics. Two hundred and fifty-one bipolar patients were separated according to their family history, 20 with a family history of mania with or without depression, 86 with a family history of depression only, and 145 with a family history of neither mania nor depression. The group that had a family history of mania was notable in that it showed more episodes of affective illness and was more likely to be readmitted to hospital. This difference in course suggests a familial association with multiple episodes and mania. In other respects than in course of illness, the groups separated by family history were similar.

Adult↗

PubMed1979

Postpartum mania.

Twenty-one patients with bipolar affective disorder (20 manic episodes, one depressive episode) during the postpartum period were evaluated. They were compared to an unselected group of womicantly more Schneiderian symptoms and fewer recurrences of illness within the three-year periofectively ill relatives than the controls. The practical significance of these findings with rey of the bipolar syndrome.

Adult↗

PubMed1979

Manic depressive illness and EEG abnormalities.

In evaluating 40 manic-depressive (bipolar) patients who had clinical electroencephalograms, there was a significant relationship between abnormal EEG findings and a negative family history for affective disorder when a comparison was made between patients with various classes of family history.

Bipolar Disorder↗

PubMedDate not supplied

A polyepisodic course in bipolar illness: possible clinical relationships.

Using archival data, we conducted a systematic study of consecutive admissions of bipolar patients and found that an early age of onset, a subacute onset, a family history of bipolarity, and the administration of electroconvulsive therapy (ECT) during an index episode were individually associated with a polyepisodic course of illness (three to nine or more episodes) during a period of observation which included onset of illness, index admission, and a period of follow-up. The family history of biopolarity which seems to predispose to multiple episodes suggests that what may be transmitted may not necessarily be a bipolar illness but possibly an illness with many episodes, thus increasing the likelihood of occurrence of a manic episode.

Age Factors↗