PubMed Health⌕ Search

Biomedical subjects

A Kahán

Publications and source records attributed to A Kahán.

14 recordsLinked to original sources
PubMed1976

The effect of ethyl apovincaminate on the circulation of the eyeground.

Ethyl apovincaminate (RGH-4405, Cavinton), contrary to the active vasodilators used up to the present, increases blood pressure of the eyeground. Dynamics of the eyeground circulation has been investigated with fluorescein angiography performed at certain points of time. Blood supply of the macula lutea was increased in the first place by Cavinton.

Blood Pressure↗
PubMed1976

Use of ethyl apovincaminate in ophthalmological therapy.

Ethyl apovincaminate (RGH-4405, Cavinton) has been administered to 100 predominantly arteriosclerotic patients to increase circulation in the eyeground. Visual acuities improved in 88 cases, by 73% in average; in twelve cases there was no change, but deterioration did not occur. Improvement was still more significant (267%) in occlusions and retinopathies associated with atherosclerosis of the central retinal artery. The dose of Cavinton was 20 mg in drop infusion or three times daily 10 mg i.v. Side-effects, if any, disappeared spontaneously upon reduction of the dose. The improvement paralleled the increases of the blood pressures in the central retinal arteries. This increase of pressure head is suggested to dilate passively the vessels.

Arteriosclerosis↗
PubMed1975

The porphyrin content of harderian glands in rats and the melatonin-melanocyte stimulating hormone-system.

Porphyrin contents of the Harderian glands were compared in groups of rats composed according to sex and age, exposed to continuous darkness or 3000 Lux illumination, or to changing natural illumination around the clock. All instances of melatonin-prevalence (e.g. absence of light, prepuberty) increased, those of melanocyte stimulating hormone decrease the porphyrin contents. Intraperitoneal injections of these hormones evoked analogous changes, followed by secondary inverse responses. Results are interpreted in terms of antagonism, equilibrium and circadian imbalance of the above hormones. Damping of the latter by the fluorescent light of the Harderian gland is suggested.

Age Factors↗