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Biomedical subjects

A Kan

Publications and source records attributed to A Kan.

26 records · Page 2Linked to original sources
PubMed1989

Heterotropic brain tissue presenting as bald cysts with a collar of hypertrophic hair. The 'hair collar' sign.

We report the cases of two children who were each noted at birth to have a single bald compressible nodule on the scalp that was surrounded by a collar of hypertrophic hair. One of the mothers had taken doxylamine succinate during pregnancy. Extensive investigations and, finally, surgery revealed that the lesions were heterotropic brain tissue without connection to the brain. Encephaloceles may also have a "hair collar." The presence of a hair collar around any cutaneous lesion should alert the clinician to the possibility of a neuroectodermal defect. All procedures on these lesions should be delayed until appropriate investigations have excluded any connection with the underlying nervous system.

Brain↗
PubMed1983

Amoebic meningitis also occurs in NSW.

The clinical, pathological and laboratory findings of a 3-year-old boy with proven primary amoebic meningo-encephalitis are described. The EEG showed changes of acute cortical necrosis lateralised to one temporal lobe and was similar to that described with Herpes simplex encephalitis. CT scan findings indicated acute cortical inflammation and basal arachnoiditis. The disease should be suspected in the context of acute pyogenic meningitis when no organisms are isolated. Treatment with amphotericin-B, miconazole and rifampicin has been effective in previously reported patients.

Amebiasis↗
PubMed1982

Primary amoebic (Naegleria) meningoencephalitis.

The computed tomographic (CT) appearance of a case of primary meningoencephalitis due to the free living amoeba Naegleria fowleri is presented. The cisterns around and above the midbrain and the subarachnoid spaces were obliterated on precontrast CT. Marked enhancement in these regions was seen after intravenous contrast medium administration. The sulci and adjacent grey matter were also strongly enhanced. The ventricular size was normal. Pathological findings were those of arachnoiditis and invasion of the leptomeninges and brain substance by amoebae, especially at the base of the brain and cerebellum.

Amebiasis↗
PubMed1981

Mandibular and para-mandibular tumors in children. Report of 16 cases.

Sixteen cases of mandibular tumors or paramandibular soft tissue tumors with mandibular involvement are reported. These include such rare mandibular tumors or tumor-like conditions as melanotic progonoma, intraosseous haematoma secondary to von Willebrand's disease, post-irradiation osteosarcoma, monostotic eosinophilic granuloma, aneurysmal bone cyst and osseous hemangiopericytoma. Three cases of cherubism, one of fibrous dysplasia or aggressive fibromatosis and one of central giant cell reparative granuloma are also reported. The soft tissue tumors comprise round cell sarcoma, parotid adeno-carcinoma with generalised metastases, embryonal rhabdo-myo-sarcoma, neuro-fibro-sarcoma and congenital cystic hygroma. In all the cases the disease was well advanced when the patient presented for X-ray examination. The specific X-ray diagnosis of mandibular and paramandibular tumors in childhood is more difficult than that of similar tumors in other parts of the body.

Adolescent↗
PubMed1981

New forms of neonatal death dwarfism. Report of 3 cases.

The term Lethal Neonatal Dwarfism (Death Dwarfism) denotes bone dysplasias which always have a fatal outcome. Three different cases of "new" forms of death dwarfism are reported. A babygram should be a routine examination in all the cases of stillborn babies or those who die soon after the birth. If then the diagnosis cannot be established microscopic investigations of the growth cartilage should be performed.

Achondroplasia↗