Biomedical subjects

A Khedim

Publications and source records attributed to A Khedim.

4 recordsLinked to original sources

PubMed2006

[Epidemiology of nasal and paranasal sinus cancer in Tunisia].

OBJECTIVE: To report the epidemiological and clinical features of nasal and paranasal sinus cancers collected during a period of 35 years at the Salah Azaiez Institute of Tunis. MATERIAL AND METHODS: This retrospective study concerned patients with histologically confirmed nasal and paranasal sinus cancers treated at our institute from 1969 to 2004. We collected the following data: age, sex, residence (rural or urban), site, occupation and professional exposure, histological type and tumor extension. RESULTS: We identified 265 cases (163 M; 102 F; Sex-ratio=1.65) with a mean age of 60 years (3 months - 91 years). Epidermoid carcinoma (47%) and adenocarcinoma (16%) predominated followed by sarcoma (14%) and melanoma (6%). We observed only 2 cases (0.7%) of ethmoidal adenocarcinoma. CONCLUSION: Nasal and paranasal cancers in Tunisia are linked more to chronic rhino-sinusal inflammation than professional exposition (wood).

Adolescent↗

PubMed2006

[Rhinocerebral mucormycosis in four diabetics].

UNLABELLED: Mucormycosis is caused by a zygomycetes fungus in a vascular location. This fungus is a saprophytic organism which can become pathogenic in specific conditions, particularly in patients with diabetes mellitus. A rhinocerebral localization is common, leading to often fatal devastating sinusitis. Positive diagnosis requires histological proof with characteristic hyphal tissue invasion. Frozen section is essential for diagnosis and management of rhinocerebral mucormycosis. MATERIAL AND METHODS: We report four cases of rhinocerebral mucormycosis in diabetic patients, two men and two women, mean age 51 years. RESULTS: Histological examination showed characteristic hyphae in a vascular localization. Treatment was systemic antifungal therapy with amphotericin B and debridement of necrotic tissue. Three patients recovered completely. One died. CONCLUSION: Rhinocerebral mucormycosis is a rare fungal infection with very poor prognosis. The aim of this study was to report the clinical and pathological features of rhinocerebral mucormycosis and to evaluate the contribution of frozen section for diagnosis and management.

Adult↗

PubMed1993

[Costa acro-kerato-elastoidosis].

We report 2 cases of acrokeratoelastoidosis of Costa observed in two sisters born of unaffected first cousins. The lesions were lenticular papules, either white or of normal skin colour, which were isolated or arranged in groups of plaques crossed by the natural furrows and located on the thenar eminences, the lateral edges of the hands and fingers and the back of the interphalangeal joints. On the feet, the lesions, located on the lateral edges, the plantar arch and the heel, were much more keratotic and appeared to be translucent. Hyperhidrosis was noted in only one of the two patients. Histological examination showed, beneath an acanthotic and hyperkeratotic epidermis, a reduced elastic network with shorter and thinner fibres in the middle dermis. These are two typical but rough cases of acrokeratoelastoidosis of Costa. The mode of transmission of this disease (autosomal recessive?) seems to be unusual compared with the data found in the literature (dominant, or sporadic cases).

Adolescent↗

PubMed1986

Problems connected with the analysis of halocarbons and hydrocarbons in the non-urban atmosphere.

The problems connected with the measurement of hydrocarbons outside urban areas are considerable: The atmospheric mixing ratios of most of the hydrocarbons are very low--from a few ppb down to some ppt; the mixture of hydrocarbons is extremely complex, ranging from light n-alkanes to alkyl benzenes and terpenes; for measurements in remote areas the logistic conditions often restrict the instrumentation which can be used for sample collection or in situ measurements (such as lack of electric power supply, weight restrictions etc.). Nevertheless, sensitive and sufficiently reliable measurements of hydrocarbons in the non-urban atmosphere are important. Hydrocarbons are important factors in the tropospheric photochemistry (e.g. ozone formation) and can be used as valuable tracers for man-made atmospheric pollutants etc. Other useful tracers for anthropogenic emission are halocarbons such as dichlormethane, tri- and tetrachloroethen etc. The impact of man-made hydrocarbons on the chemistry of the troposphere can only be understood if the extent of natural (biogenic) contributions is known. From measurements of a large variety of hydrocarbons and halocarbons it is often possible to obtain information about the sources of the most important atmospheric hydrocarbon species, even for trace gases with both significant anthropogenic and biogenic sources. In this presentation some of the problems and their solutions connected with such measurements of atmospheric hydrocarbons and halocarbons are presented and discussed. Some of the results obtained by several series of measurements are described, indicating that man-made as well as biogenic hydrocarbons can be important factors for the chemistry of the atmosphere.

Air Pollutants, Occupational↗