Biomedical subjects

A Kierzek

Publications and source records attributed to A Kierzek.

At least 19 recordsLinked to original sources

PubMed2001

[Attempts at surgical treatment of nasal septum deformities in the XIX century with instruments powered by an "electric motor"].

The methods of surgical treatment of nasal spetum deformations by electrical instruments in the XIX century were used especially in United States of America. In the begining of seventieth of the XIX century D.H. Goodwillie used the machine by foot. In the half of eightieth of the XIX century and later the nasal trephine was used by C. Astier, W. Wróblewski, J. Wright, M. Schmidt, J. Wolff, F. Kretschmann and others, G. Spiess employed the special protected speculum. The special saws were also in prewailing use (G. Spiess and others). Those methods were generally not many effective.

Electric Power Supplies↗

PubMed2000

3-Methyladenine-DNA glycosylase I from Escherichia coli-computer modeling and supporting experimental evidence.

TagA (3-methyladenine-DNA glycosylase I) excises 3-methyadenine and 3-methylguanine from alkylated DNA. The structure of this enzyme has not yet been determined experimentally. We propose a three-dimensional model of the TagA protein based on the threading algorithm. The model shows that TagA is a mostly alpha-helical protein, in agreement with circular dichroism measurements. None of the eight cysteines present in the TagA sequence forms a disulfide bridge in the model structure, which has also been experimentally verified with the use of Ellman method.

Algorithms↗

PubMed2000

[Professional education of Polish physicians in otologic centers of Vienna in the 19th century].

The foundations of the modern otology in Vienna created Adam Politzer, Joseph Gruber, Victor Urbantschitsch. The professional and scientific achievements of Joseph Gruber and Victor Urbantschitsch are described briefly. Gruber was one of two heads of otiatric clinic in Vienna. Urbantschitsch was an authority of psychophysiology of hearing. Such well-known otologists in Vienna as Gustav Alexander, Robert Bárány, Beniamin Gomperz, Erich Ruttin and others were a good teachers of many foreign physicians also from Polish territories. Robert Bárány was a Nobel prize winner.

Austria↗

PubMed2000

[The achievement of Warsowian physicians in otolaryngology after introduction of laryngoscopy].

The professional and scientific activities of Konstanty Karwowski (1834-1918), one of the pioneers of the laryngoscopy in Warsaw are described. The widespread contacts of Ignacy Baranowski (1833-1919) with the Viennese scientific medical world are stressed. The beginning of otological lectures by Wiktor Szokalski (1811-1897) in 1864, the famous Polish ophtalmologist is mentioned. The achievements of eminent Polish surgeons: Aleksander A. Le Brun (1803-1868), Hipolit Korzeniowski (1827-1897), Polikarp Girsztowt (1827-1877) and Julian Kosiński (1833-1914) from surgical clinics in Warsaw are presented. The first total laryngectomy in Poland, performed by Kosiński in 1877 is presented in detail.

Achievement↗

PubMed2000

[The importance of Adam Politzer for the Polish otiatrics].

The difficult start of world otiatrics is described. The importance of Adam Politzer (1835-1920) and Joseph Gruber (1827-1900) in the origin of otiatric clinic in Vienna is depicted. The professional and scientific career is described of Politzer with a wide experiences with the educational otiatric institutions abroad. He was the author of many scientific papers and books. His best-known contribution to clinical otology is his inflation of the middle ear by "politzerization". He contributed to knowledge in every department of otology especially in the surgical treatment of endocranial complications of aural diseases. Politzer was a constructor of many otological instruments. He was also a lover of fine arts. The impressions of Samuel Meyerson (1851-1939), a Warsaw physician from the Politzer's clinic are described in detail.

Ambulatory Care Facilities↗

PubMed2000

[Struggles with nasal septum malformations in the XIX century].

The maxilla-premaxilla approach to extensive nasal septum surgery performed in 1959 by M.H. Cottle and all is a obligatory method today. The struggle with a nasal septum deformations from the half of eighteenth of XIX century is presented (S.T. Quelmaltz). The correction of nasal septum by "the compression method", usually the vain method performed by A. Jurasz sen., P.L-B. Guersant, M. Warren, E.P. Chassaignac, F. Petersen and others are described in detail. The willful nasal septum perforation was performed by P.F. Blondin and P.T. Rupprecht. The special forceps were used by A. Jurasz sen. and R. Adams. The dorsum nasal cut was performed by J.N. Demarquay and B.R. Langenbeck. The destruction of inferior nasal concha was performed by M. Mackenzie and P. Delavan. The employment of galvanokauterization and electrolysis by A. Jurasz sen., F.E. Voltolini, C. Miot and E.M. Moure is mentioned. A description of fenestrated resection of septi nasi by Krieg in 1886 and then modified by G. Killian is presented.

Europe↗

PubMed2000

[Training of Polish physicians in rhinolaryngology in XIX century Vienna].

The eminent Viennese rhinolaryngologists in the XIX century were: Leopold Schroetter, Karl Stoerk, Johann Schnitzler, Ottokar Chiari, Markus Hajek and others. Stroerk, the pupil of Ludwig Türck was a head of rhinolaryngological clinic since 1891, he was also the author of valuable papers, among other things on rhinoscleroma. Schnitzler, the assistant of Johann R. von Oppolzer was a head of Viennese polyclinic. The therapeutical nihilism in Viennese clinics is mentioned. Ottokar Chiari, the assistant of Schroetter was an eminent rhinolaryngologist. Markus Hajek was a head of otorhinolarynoglogical clinic in Vienna performed in 1919. Theodor Billroth, professor of surgery in Vienna was the first to remove the larynx for cancer in 1873.

Austria↗

PubMed2000

[Leopold Schroetter von Kristelli and Polish laryngologists].

The researches of Leopold Schroetter von Kristelli, Karl Stoerk, Johann Schnitzler, Ottokar Chiari, Markus Hajek and others, the best Viennese rhinolaryngologists clarified our knowledge on rhinolaryngology. Leopold Schroetter, the famous rhinolaryngologist and internist, was a head of rhinolaryngological clinic in Vienna. He is shown as a precursor of treatment tracheas stenosis, he was also the author of many scientific papers and several books, coeditor of scientific medical magazines, a good teacher of a great number of physicians also from Polish territories. The Polish doctors: Samuel Meyerson, Władysław Rudnicki and Alfred M. Sokołowski were a reporters from Schroetter's clinic.

History, 19th Century↗

PubMed1999

[The otolaryngological pilgrimage of Polish physicians to Vienna in the 19th century].

The conditions of studying and specialistic training of Polish physicians at Vienna University in the 19th century are presented briefly. The teaching methods at Vienna University by professors, assistant professors and assistants are outlined. The origin and development of polyclinic in Vienna (Allgemeine Poliklinik) is described in detail. The therapeutical nihilism in Viennese clinics at that time is mentioned. The enumeration of such famous scientists in otiatrics and rhinolaryngology in Vienna in the 19th century as Adam Politzer, Joseph Gruber, Victor Urbantschitsch, Leopold von Schroetter, Karl Stoerk, Johann Schnitzler is pointed out finally.

Austria↗

PubMed1999

[Otolaryngologic hospital wards and out-patient clinics in Warsaw in the second part of the XIX-th and the beginning part of the XX-th century].

The origin of the first otolaryngological hospital wards in Warsaw: laryngological ward of St. Roch Hospital and otological ward of Ujazdowski Hospital, both founded in 1881, and laryngological out-patient clinic at St. Spirit Hospital, founded in 1883, is described. The rise of the first otolaryngological hospital ward in Warsaw Orthodox Jew Hospital established in 1903 is thoroughly described. The activity of Warsaw hospital wards and hospital out-patient clinics at Infant Jesus Hospital, the Warsaw Hospital for Children, the Berson and Bauman Hospital, the Wolski Hospital, the Blessed Virgin Mary Hospital, the Evangelical Hospital, the Charles and Mary Hospital for Children, the Warsaw Municipal Lazaret is presented in detail.

History, 19th Century↗

PubMed1999

[A Polish physician's impressions from the Viennese Clinic of Winternitz].

The achievements of Vincenz Priestnitz, Sebastian Kneipp and Wilhelm Winternitz for the development of hydrotherapy are presented at the beginning. The professional and scientific activities of Winternitz are strongly pointed out. Eugeniusz Piasecki (1872-1947), the Polish physician and theorist of physical education impressions from Vieneese Clinic of Winternitz are depicted widely. The role of Winternitz in formation of modern hydrotherapy in Polish territories is presented finally.

History, 19th Century↗

PubMed1999

[How a Warsaw physician helped Sienkiewicz in his literary debut].

This article is on the borderline between history of medicine and history of literature. The life and works are presented of Konrad Dobrski (1849-1915), with description of his works in Warsaw and scientific visits to Vienna. He was a well-known Warsaw's physician, especially in laryngology and pulmonology. His friendly relations with Henryk Sienkiewicz, a famous Polish writer, in adolescence are described in more details. The Dobrski's participation in origin of first Sienkiewicz's novel "Na marne" is presented with full particulars. The Józef Ignacy Kraszewski's assistance in this matter is also depicted.

Drama↗

PubMed1998

[The organization and activity of the otolaryngological institutions in Warsaw in the second half of the 19th century and at the beginning of the 20th century].

The importance of various otolaryngological institutions: hospital wards, outpatient clinics, infirmaries and consulting rooms in the formation of the new specialization, otolaryngology, is described in this paper. An important role of surgery in the first period of the development of otolaryngology is mentioned. At that time all major otolaryngological operations were performed by general surgeons. The necessity to create new separate hospital otolaryngological wards became evident. The attainment of general surgical education and management of suitable post-operation treatment by otolaryngologists as well as creation of autonomous operating rooms were also evident. Poor state of Warsaw otolaryngological outpatient clinics is described in detail. The state of otolaryngological institutions in Europe, in the United States of North America and in the Kingdom of Poland is described briefly.

Ambulatory Care Facilities↗

PubMed1998

[The participation of the Warsaw otolaryngologists in medical conferences and congresses in the 19th century].

The participation of a famous Polish laryngologist Teodor Heryng (1847-1925) in many scientific congresses was presented in separate publications. Many Varsovian otolaryngologists also took part in a great number of international congresses. Jan Sedziak's (1861-1932) participation in international congress in Vienna in 1908 on account of the 50th anniversary of the invention of laryngoscopy by Manuel Garcia is stressed. Sedziak was specially esteemed in Great Britain and in the United States of North America. Very significant contribution of Alfred M. Sokołowski (1849-1924) to the medical congress in Rome in 1894 is described. The widespread contacts of Varsovian otolaryngologists: Zdzisław Dmochowski, Feliks Erbrich, Leopold Lubliner, Edmund Modrzejewski, Zygmunt Srebrny. Jan Szmurło, Witold Szumlański with the European scientific world are mentioned, as well as their active participation in many medical meetings and congresses.

Congresses as Topic↗

PubMed1998

[A little about the nineteenth-century history of a health resort in Ciechocinek].

Impression of a Warsaw physician, hygienist and social worker Ludwik Natanson (1822-1896) from his journey to Ciechocinek in 1853 was reported. Brief history of this resort as well as contemporary indications and contraindications to treatment there were described. A role which in creation of this resort was played by Roman Ignatowski (1805-1889), who was a resort-doctor for many years, was presented.

Health Resorts↗

PubMed1997

The genetic stability of potato spindle tuber viroid (PSTVd) molecular variants.

RNA viruses propagate as a population of genetically related entities composing a quasi-species. Specific representatives are the result of both a high mutation rate during replication and competition between the continuously arising sequence variants. Similar to other RNA pathogens, potato spindle tuber viroid (PSTVd) propagates as a population of similar but nonidentical sequences. The sequence of progeny molecules derived from cloned molecular variants of PSTVd were studied after one and six consecutive plant passages. Although the severe parental sequence S23 was found to be genetically stable, all five other parental sequences analyzed, irrespective of their pathogenicity, led to the appearance of complex populations. Divergence of the progeny was observed at the sequence level, but also, more surprisingly, at the level of the pathogenicity of individual progeny molecules. In two cases, the parental sequence was retained in the progeny population. In the other cases, it was completely out-competed and eliminated, sometimes in as little as one plant passage. Although it has been observed previously that artificially mutated PSTVd molecules may revert rapidly to the wild-type sequence, this study presents direct evidence for the rapid evolution of naturally occurring PSTVd sequence variants.

Base Sequence↗

PubMed1997

Energy minimization of globular proteins with solvent effects included. Comparison of empirical solvation energy terms and explicit water treatment.

The effect of an empirical solvation energy term on energy minimization of ribonuclease T1 was established using different sets of Atomic Solvation Parameters. The results are compared to minimization in vacuo and in a 10 A water shell. The best solvent model as judged from the comparison to the crystal structure was an empirical solvation potential derived from free energies of transfer of amino-acid side-chain analogues from vapour to water. The use of this model causes, however, energy and gradient oscillations, which make it inapplicable with standard protocols of molecular dynamics simulations. The empirical solvation model which was found by other authors (von Freyberg et al., 1993, J. Mol. Biol. 233, 275-292) to give good results in the NMR structure refinement led to distortions of the ribonuclease native structure. The model based on statistical analysis of crystal structures did not perform better than minimization in vacuo.

Hydrogen Bonding↗

PubMed1997

[How was Polish phoniatrics born? (Part III. Jan Siestrzynski, Jozef Frank)].

The last years of Jan Siestrzyński (1788-1824), the first Polish phoniatrist, as a military physician at Końskie are presented. Siestrzyński was the author of a book of "Teorya i mechanizm mowy..." ("Theory and Mechanism of Speech..."), published in 1820. This book was the fundamental work of his life. The publications by Trompeo (1820), Borthwick (1836) and Brück (1856) dealing with similar problems dated later made Siestrzyński one of the first pioneers of European phoniatrists. Siestrzyński's book "O litografii" ("On litography" is briefly presented. The achievements of Józef Frank (1771-1842), who was a professor of Vilnius University, in popularization of the knowledge about speech disorders (especially in his book "Praxeos medicae universae praecepta" were pointed out).

History, 18th Century↗