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Biomedical subjects

A Kitamura

Publications and source records attributed to A Kitamura.

At least 145 records · Page 8Linked to original sources

Serum fatty acids and fish intake in rural Japanese, urban Japanese, Japanese American and Caucasian American men.

To examine the relationship of fish intake with serum fatty acids cross-culturally, we surveyed a total of 136 men aged 34 to 55 years in four different populations: rural Japanese (RJ), urban Japanese (UJ), Japanese Americans (JA), and Caucasian Americans (CA). Mean levels of estimated total fish intake per day were 124.9 g in RJ, 70.8 g in UJ, 45.7 g in JA, and 32.3 g in CA. The percentage of total serum fatty acids contributed by omega-3 polyunsaturated fatty acids in these populations was 11.8% in RJ, 9.0% in UJ, 3.4% in JA and 2.5% in CA. Means of omega-3 fatty acids and intake of fish were correlated at the population level; this relationship was strongest when intake of dark-meat fish was considered (n = 4, r = 0.979, p = 0.02). Within each population, except for UJ, individual omega-3 fatty acid levels and dark-meat fish intake were significantly associated (p less than 0.05). A 20 g increase in dark-meat fish consumption was associated with an estimated relative increase in omega-3 fatty acid content of serum by 0.76% in RJ, 0.75% in UJ, 0.64% in JA, and 0.22% in CA. The association between fish intake and serum omega-3 fatty acids at the individual level was not explained by other coronary risk factors. Mortality from coronary heart disease is much lower in Japan than in the US. Population differences in fish intake and serum omega-3 fatty acid levels may contribute to the population difference in the risk of coronary heart disease.

Adult↗

Stereotactic aqua stream and aspirator for hypertensive intracerebral hematoma.

The stereotactic aqua stream and aspirator (SAS & A) is a modification of the aqua stream and aspirator (AS & A) designed for stereotactic evacuation of intracerebral hematoma. The needle of the new instrument is inserted into the brain through a burr hole by a conventional stereotactic technique and its tip is directed to the center of the hematoma. The hematoma is broken up with a stream of saline solution from a nozzle. Fragments of clot and fluid can then be aspirated piecemeal through the suction tube. The postoperative CT images show successful evacuation of the hematoma, and the clinical evaluation also showed satisfactory results. This instrument can be used safely, without any complications, early after the stroke.

Aged↗

Trends for coronary heart disease and stroke and their risk factors in Japan.

Disease surveillance and population surveys of risk characteristics in a northeast rural community of Japan (1965 census population, 7,030) are combined in an attempt to relate morbidity and risk factor trends for coronary heart disease and stroke during the last 2 decades. Between 1964 and 1983, the incidence of coronary heart disease (i.e., combined myocardial infarction, angina pectoris, and sudden death) did not change significantly among men and women ages 40-69, and was lower than that for stroke. The incidence of all stroke declined about 60% for both men and women, ages 40-69, with a significant decrease in cerebral hemorrhage for both sexes and in cerebral infarction for men. Between 1963-1966 and 1980-1983, significant upward shifts occurred in the means and distributions of serum total cholesterol and serum total protein in every age and sex group, primarily during the 1st decade. Age-adjusted mean cholesterol levels rose 22 mg/dl to the 1980-1983 mean of 179 mg/dl in men ages 40-69. In women ages 40-69, the mean rose 29 mg/dl to 192 mg/dl. Among nutrients, animal fat intake doubled in men ages 40-59 from 4.5% of daily calories in 1969 to 9.6% in 1980-1983. Animal protein intake also increased, from 5.8% to 7.1%. Most of this increase occurred between 1969 and 1972-1975 and may be attributable to an increased intake of meat, eggs and dairy products. From 1963-1966 to 1980-1983, mean relative weight index rose significantly for all age-sex groups except men ages 50-69. Mean systolic and diastolic blood pressure levels declined for every age-sex group, with a 15-mm Hg age-adjusted decrease in systolic, 4-mm Hg decrease in diastolic pressure among men ages 40-69, and a 11-mm Hg systolic and 4-mm Hg diastolic decrease for women. Two cohorts of men and women ages 40-69 at baseline were followed for disease incidence: an early cohort (2,257 persons) followed from 1963-1966 to 1973 and a later cohort (2,711 persons) followed from 1972-1975 to 1983. In these cohorts, significant risk prediction for cerebral hemorrhage and infarction was obtained with blood pressure level and end organ effects in the electrocardiogram and fundus photographs. Serum cholesterol was inversely associated with cerebral hemorrhage in the early cohort but not in the later.(ABSTRACT TRUNCATED AT 400 WORDS)

Adult↗

[Removal of hypertensive intracerebral hematoma with stereotactic aqua-stream and aspirator (SAS & A)].

The stereotactic aqua-stream and aspirator (SAS & A) was a modification of the aqua-stream and aspirator (AS & A) in order to remove hypertensive intracerebral hematoma. The newly designed needles were held with an adaptor to any kind of Leksell's, Patil's, UT's, Sugita's, or Komai's stereotactic equipment. The needles were stereotactically inserted into the center of the hematoma cavity through a burr-hole. The needles were composed of an outer tube and two inner tubes. The inner tubes were arranged parallel with each other. One was an irrigation tube of 0.1 mm in inner diameter, the other was a suction tube of 2 mm in outer diameter. The blood clot was sucked through a window of the outer tube by the aspirator and incarcerated there soon after. The incarcerated blood clot was crushed by a small streak of saline solution from the nozzle of the irrigation tube. Crushed clot and fluid were sucked through the suction tube. The extent of evacuation of the hematoma was evaluated by CT scans during stereotactic surgery. In all 10 cases of hypertensive intracerebral hematoma, 73-98% of hematoma content was removed. Disturbances of consciousness recovered soon after the surgery. Aphasia and hemiparesis improved later. Hard clot could be removed completely and safely by this new instrument, SAS & A, at an early stage after a stroke, because of the crushing and washing action.

Aged↗

[AS & A (aqua-stream and aspirator) in neurosurgery: comparison with laser and CUSA].

A new instrument, the aqua-stream and aspirator (AS & A) is useful and safe for microscopical neurosurgery. The apparatus is simple and small. The handpiece is small and light as well as being easy to manipulate. Sterilization is easy and safe. Both streaming and aspirating tubes of AS & A are thin, so that operative field is not obstructed by the operative microscope. The operative field is kept dry and clean by means of washing the work of AS & A. It is economical, because less gas and saline solution than usual are needed during the usual craniotomy (a one liter soft bottle). It is superior to laser and CUSA for the removal of deeply seated soft tumors.

Adolescent↗

A case of oromandibular-digital hypogenesis syndrome.

The oromandibular-digital hypogenesis syndrome is characterized by failure of development of the intraoral region and the distal extremities. A 12 year old female with an anomaly of the lingual fraenum, hypodontia of the lower incisors and defective fingers and toes was referred to our clinic. The aetiology of the disorder is still obscure. The author has reviewed the literature and discusses the morphological variation of the lingual fraenum.

Abnormalities, Multiple↗

[A case of amebic liver abscess rupturing into the stomach].

A forty-eight year-old man complained of upper abdominal pain and diarrhea with mucinous bloody stool. He had not been abroad. Except high fever, anemia, leukocytosis and elevated rate of erythrocyte sedimentation, laboratory findings were not abnormal. Gastrofiberscopy showed the protrusion of gastric mucosa with a hollow on its surface in the angle. Abdominal CT scan and echogram revealed an abscess in the right hepatic lobe and an abscess in the left lobe. Ulceration and small protrusion of the rectal mucosa were found by romanoscopy. Stool examinations could not reveal amebas, but serological test for amebiasis by the Ouchterlony method showed positive. Under the diagnosis of the perforation into the stomach of amebic liver abscess, he was treated with Metronidazole and tetracycline. But, as a diffuse shadow appeared in the right thoracic cavity on the chest x-ray films with bloody sputa, perforation of amebic liver abscess to the right thoracic cavity was suspected. Laparotomy showed the communication of the abscess to gastric lumen. The post operative course was uneventful. We reported a case with the rare complication of amebic liver abscess.

Humans↗

Homotypic pair formation during conjugation in Tetrahymena thermophila.

In the ciliate Tetrahymena thermophila, conjugation has been believed to occur only between cells of different mating types. We found the formation of homotypic pairs during normal conjugation by using micronuclear morphological markers. Homotypic pairs formed preferentially during the first 10 min following the first pair formation and comprised about half of the pairs. These results suggest the involvement of mating-type non-specific adhesion of cells in the initial step of conjugation. Homotypic pairs apparently persist for at least 30 min and then separate into single cells. Homotypic pairs are also formed when conjugant pairs re-form after mechanical separation of heterotypic pairs. Five kinds of glycosidases, three kinds of proteases and phospholipase C showed no effect on either the formation of homotypic pairs of their separation. The relation between the mating-type substances and the molecules responsible for mating-type non-specific adhesion of cells is discussed.

Animals↗