Biomedical subjects

A Klemetti

Publications and source records attributed to A Klemetti.

33 records · Page 2Linked to original sources

PubMed1978

Congenital defects in a cohort followed for seven years.

A geographically limited cohort of Finnish children was followed from birth for seven years, and all congenital abnormalities were recorded and classified and special attention was given to the cumulative detection rate, and the time of detection of various defects. Of 3674 pregnancies 135 babies with or without defects were stillborn or died during the neonatal period. The remaining 3539 were followed up to seven years, when the percentage follow-up was 81.7%. Detailed information on 76 malformed livebirths registered in the neonatal period was available in 63 cases (82.9%). The diagnosis was found to be incorrect in 6 cases and additional defects were registered in 7 of these children. Additional congenital abnormalities detected in the follow-up study were divided into three groups: all congenital disorders or abnormalities with prenatal etiology (248 children), all congenital defects (111 of these 248) and structural malformations (31 of these 111). The cumulative detection rates in these groups increased with time and at the end of the study when the children were aged seven were 9.4%, 5.6% and 2.6%, respectively.

Abnormalities, Multiple↗

PubMed1977

Definition of congenital malformations and detection of associations with maternal factors.

Data collected from a cohort of 2913 pregnancies were analyzed to determine whether the varying definitions of congenital malformations influence the statistical result in the search for possible etiological factors. According to three different definitions of congenital malformations, three study groups were formed, i.e. structural malformations, all congenital defects, and all disorders or abnormalities with possible prenatal etiology. These consisted of 93, 197 and 334 cases, respectively. The control group consisted of 2579 cases. Positive associations were noted between the study groups and some factors concerning pregnancy, and the social history of the parents. The associations were strongest in the group of structural malformations and became weaker when this group was 'diluted' by other defects with questionable prenatal origin. Hence, when comparisons for evaluating the causality of significant associations in different materials are made, the definition of the concept of congenital malformations should be taken into consideration.

Adult↗

PubMed1975

Screening for neonatal hearing disorders in the Province of Central Finland.

Screening for congenital hearing disorders in newborn infants has been carried out in the Province of Central Finland since 1967. In 1967-1971, a total of 23 children (12 boys and 11 girls) were found to have congenital hearind disorders. From this it can be calculated that 90 infants are born each year with congenital hearing disorders in Finland. Our sample did not include slight or moderate hearing disorders (under 45 dB). 11 children under the age of 18 months were provided with a hearing aid. In spite of the screening, 12 cases (mean age 2 years) were not diagnosed until they came to the phoniatric clinic because of delayed speech development. These children were presumably also congenitally deaf. Most of the children in the delayed group reacted favourably to the auropalpebral reflex test on the obstetrical ward; their speech development was better and they also profited more from having a hearing aid than those children whose hearing defect had been discovered earlier. Screening for hearing disorders should be made nation-wide in order to avoid the harmful effects of the delay of rehabilitation on the child's development. The possibility of a hearing disorder should be kept in mind in those cases where there is a delay in speech development and also in those cases where the child has some other severe congenital defect which demands the attention of the nursing staff.

Child, Preschool↗

PubMed1974