LETTERS TO THE EDITOR: Reply.
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Biomedical subjects
Publications and source records attributed to A Komaroff.
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The complexities of the chronic fatigue syndrome and the methodologic problems associated with its study indicate the need for a comprehensive, systematic, and integrated approach to the evaluation, classification, and study of persons with this condition and other fatiguing illnesses. We propose a conceptual framework and a set of guidelines that provide such an approach. Our guidelines include recommendations for the clinical evaluation of fatigued persons, a revised case definition of the chronic fatigue syndrome, and a strategy for subgrouping fatigued persons in formal investigations.
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While a protocol is generally used by a physician, it is important for the manager to understand its use in monitoring costs and in assuring conformance with defined optimal standards of care.