PubMed Health⌕ Search

Biomedical subjects

A Kopacz

Publications and source records attributed to A Kopacz.

At least 19 recordsLinked to original sources
PubMed1992

[Level of estrogen receptors (ER) as a function of histological malignancy stages of tumors in patients with breast neoplasm].

The presence of estrogen receptors (ER) has been studied in 70 patients with primary operable breast cancer. The tumors were graded histologically according to Bloom and Richardson criteria. A significant correlation was found between these two prognostic factors: the better--differentiated tumors (I + II histological grade) had significantly higher level of ER than that in the poor--differentiated tumors. Estrogen receptor content of primary breast cancer as a function of tumor grade can be useful in selection of the most efficient treatment modalities for individual patients.

Adult↗
PubMed1989

[Lymphangiosarcoma of the leg following radiotherapy for cervical carcinoma].

A case of lymphangiosarcoma of lower extremity was observed in a female aged 68 years who had had radiotherapy for cervical carcinoma. The late therapeutic result was bad, and this indicates the necessity of radical management, that is amputation in hip joint already in an early stage of the disease, although this decision is extremely difficult for the physician.

Aged↗
PubMed1989

Cytogenetic findings in two synovial sarcomas.

Cytogenetic analysis was performed after short-term tissue culture of two recurrent synovial sarcomas. The tumors were classified on the basis of morphology, location, and immunohistochemistry. In a poorly differentiated tumor, the karyotype 49,XY, +7, +8, +19,t(5:18) (q11.2;q11.2), and in a biphasic tumor two clonal cell lines with common translocations t(X;18)(p11.2;q11.2) and t(12;17)(p11.2;q11.2) were present. In the predominant cell line several other structural aberrations including t(1;12)(q21;q24.3), t(3;18)(p23;q21), and 17p+ were found. A comparison of our results with previously published studies suggests that in addition to t(X;18), translocations of chromosome 18 with other chromosomes may represent a consistent feature of chromosomal changes in synovial sarcoma.

Adult↗
PubMed1980

Some aspects of cell-mediated hypersensitivity in patients with melanoma.

Cell-mediated hypersensitivity in 64 patients with melanoma was assessed by delayed-type skin reactivity to dinitrochlorobenzine (DNCB) and tubercullin as well as by lymphocyte enumerations. The immunological status of the patients was correlated with their clinical stage. The mean absolute and percentage counts of E rosette forming cells were lower in patients than in normal controls. Patients with distant metastases showed lower levels of E rosette forming cells than the patients with localized disease. No differences were found in number of EAC rosette forming cells between melanoma patients and controls. The mean absolute and percentage counts of null cells in melanoma patients in stages II and III were significantly higher than those in controls. Melanoma patients showed reduced skin reactivity to DNCB and normal reactivity to tuberculin. Patients with positive DNCB reactivity showed significantly higher total lymphocyte counts and higher percentages of E rosette forming lymphocytes than patients unreactive to DNCB.

Adult↗