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Biomedical subjects

A Kopecký

Publications and source records attributed to A Kopecký.

At least 19 recordsLinked to original sources

[Abnormal placement of the testes].

The authors defined a uniform classification of abnormal positions of the testes. They recommend also a uniform therapeutic procedure: after the first year of life treatment with human chorionic gonadotropin in one or two curves, if orchiopexy fails.

Cryptorchidism

[The effect of increased production of androgens on the development of body build morphology. Case report of an androgen-active tumor in a monozygotic twin].

The authors present an account on monozygotic twins where in one girl an androgen-active adenoma of the adrenal cortex during early puberty led to the development of the Morphogram of Body Build (Case-report of throughout the period of investigation intact from the hormonal aspect. Four years after resection of the tumour endocrine and anthropometric characteristics of the two sisters were evaluated: the hormonal status of both is normal, the somatic differences are manifested by a different final height, biacromial width and chest circumference. The results are conceived as a precedent for evaluation of risks associated with administration of anabolic steroids in children.

Adenoma

[Rheumatic fever in a developing country in North Africa].

In a catchment area with population of approximately 60,000 in Libya for a period of two years and three months a group of 38 children aged 7-12 years with the diagnosis of rheumatic fever was followed up. An incidence of cca 60 attacks of rheumatic fever per 100,000 children per year was recorded. The clinical picture of primary attacks did not differ from the clinical picture of primary attacks in technically advanced countries in the sixties and also the development of the finding on the heart in rheumatic patients with penicillin prophylaxis was equally favourable.

Adolescent

The role of the hypophysis in the regulation of the daily rhythm of aldosterone secretion.

In 12 patients treated with prednisone for more than two months, the daily rhythm of aldosterone secretion was disturbed during treatment as well as in the first week after discontinuing the therapy. The secretion of aldosterone was at the lower limit of the normal range. The daily rhythm of aldosterone secretion became normal earlier than the rhythm of 17-hydrocorticosteroids, approximately at a time when ACTH secretion became normal. A shift in maximum aldosterone secretion from morning to the afternoon or evening hours was observed in eight patients as early as on the third day of dexamethasone administration. A similar disturbance in the daily rhythm of aldosterone secretion was found in five of six patients with pituitary dwarfism.

Adolescent