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Biomedical subjects

A Koseki

Publications and source records attributed to A Koseki.

5 recordsLinked to original sources

[Investigation into the actual condition of outpatients. I. The environmental and oral health status prior to and at the first visit. Comparison of the results between present study and last investigation].

The purpose of this paper was to investigate the actual status of environmental and oral health conditions prior to and at the first visit of the outpatients who visited the pedodontics clinic of Tohoku University Dental Hospital during the period from April 1981 to May 1986, and to compare them with the results of the same kinds of investigation carried out 10 years ago. The subjects were 895 children, with questionnaires being filled out by their mothers. The following results were obtained. 1) As to methods of nursing, breast feedings have increased, while bottle feedings have decreased. The weaning period of almost all of the children was a period between 3 and 6 months of age, as the same as found during the last investigation. 2) The number of children who had eating and drinking habits at bedtime decreased relatively compared with the last investigation. 3) The majority of the children ate between meals twice a day regularly, eating fruits, senbeis (rice crackers), potato chips, and drinking milk frequently. These tendencies in the present study were almost the same as the results of the last investigation. 4) The number of children brushing more than twice a day has been increased compared with the last investigation, and most of them have been brushing their teeth after breakfast and before going to bed. 5) About 87% of the mothers of the patients thought that dental caries are an illness, but 8.9% of them did not. 6) As to caries prevention at home, the majority of the mothers were concerned about tooth-brushing habits and eating habits between meals. In conclusion, this study indicated that concern about oral health of mothers has increased in recent years.

Attitude to Health↗

[Investigation into the actual condition of outpatients. II. Correlation between the daily habits of eating and toothbrushing and the prevalence of dental caries incidence].

The purpose of this paper was to investigate the correlation between the daily habits of eating and tooth-brushing and the prevalence of dental caries in the outpatients who visited the Pedodontics Clinic of the Tohoku University Dental Hospital during the period from April 1981 to March 1986. The subjects were 877 individuals with questionnaires which the mothers had filled out. The following findings were obtained. 1) The dft index for children aged 1 year to 6 years in the present investigation was lower than that of the same age group investigated 10 years ago. 2) The dft indicies according to each feeding group were 8.86 in the bottle feeding group, 7.51 in the breast feeding group and 6.77 in the mixed feeding group. 3) The group in which the weaning period was late showed a significantly high dft index. 4) The dft index of the group taking beverages containing sugar before going to bed was significantly higher than that of the group without doing this. 5) The group of patients aged 2 years to 5 years who had between-meal snacks more frequently showed a high dft index. 6) The irregularity of the between-meal eating times caused a high tendency toward caries occurrence. 7) The group having between-meal snacks while playing showed a significantly higher dft index than that of the group having it at a table and not playing. 8) No relation was observed between the frequency of tooth brushing and the dft index.

Breast Feeding↗

[Age-related decrease of 11C-N-methylspiperone in vivo binding to human striatum detected by PET].

The effect of aging on 11C-N-methylspiperone binding to living human striatum was demonstrated using positron emission tomography. The 11 normal volunteers (22 to 72 years old) participated in this study. The uptake of 11C-N-methylspiperone in the brain following intravenous injection was highest in the striatum in individual subject. And the uptake in the striatum only gradually increased until the end of the study. The uptake of 11C-N-methylspiperone in cerebellum peaked within 10 minutes following injection and then rapidly dropped. The association rate constant "k3" was calculated from the slope of the radioactivity-ratio of striatum to cerebellum versus the equivalent time. The equivalent time was calculated from the radioactivity of cerebellum as an input function. The exponential decrease of the k3 value with aging was observed. The k3 value of the youngest subject (22 years old, male) was 0.035/min, while that of the oldest one (72 years old, male) was found to be 0.020/min. These data suggested that the dopaminergic activity through D2 dopamine receptors reduces with aging in human striatum.

Adult↗