[Vaginal metroplasty].
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Abortion, Habitual↗
Biomedical subjects
A Kosmowski
Publications and source records attributed to A Kosmowski.
[Incidence of female gonorrhoea in relationship with inflammatory gynaecological diseases - verification from cultures (author's transl)].
Gonorrhoea was detected in 7.3 per cent of 423 patients with gynaecological inflammations. Positive findings were recorded from 8.5 per cent of 248 patients with adnexitis and 6.9 per cent of 130 patients with fluor. However, gonorrhoea incidence among 31 patients with pointed condyloma was as low as 3.2 per cent. These findings were found to differ drastically from the data so far obtained from the common approach of microscopic diagnosis by which hardly any positive detection of gonococci had been recordable from gynaecological out-patients over the years. The present considerable rise in positive findings has resulted only from the use of a modified transport medium, according to Stuart, which proved to be highly applicable to gynaecological practice. With the authors' patients, the new approach showed the presence of gonorrhoea in one of 14 patients with inflammatory gynaecological processes. Against the background of the present epidemiological situation, verification of gonococci from cultures should be made an integral component of gynaecological routine checks.
Adolescent↗
[Chromosome aberrations in oncobiogram - cytogenetic studies into aberration frequency following trenimon treatment in vitro (author's transl)].
Quantitative determination of qualitatively unequivocal signs for an individual oncobiogram is difficult. However, the use of a properly standardised analysis of chromosomes may offer a possible approach to the problem. Sixty-nine tissue cultures were prepared from 15 ovarian carcinomas, and 56 of them under went sufficient growth. A concentration of 2 . 10(-7) moles/l of trenimon was added to the tissue culture for one hour. Sixteen tissue cultures were used as controls. Chromosome preparation was achieved with good success after recovery periods between five and nine hours. A total of 2,890 mitoses was evaluated. Trenimon increased the amount of damaged mitoses from 1.2 per cent to eleven per cent, while the number of aberrations was aggravated even by the factor of 6.6. - The differences were statistically secured with high significance. Some of the cell cultures suffered rises in aberration frequency by 50 per cent and even 190 per cent. Such extreme values obviously suggest the presence of extraordinary sensitivity which be utilised for cytogenetic oncobiogram.
Cells, Cultured↗