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Biomedical subjects

A Kotłowski

Publications and source records attributed to A Kotłowski.

13 recordsLinked to original sources
PubMed2001

[In vitro resistance of Candida species to antifungal agents].

The purpose of this study was to determine the in vitro susceptibility to 6 antifungal agents of 143 strains of Candida species isolated from 545 patients with suspicion of fungal infection. Test ATB Fungus (bioMérieux) was used. Among all Candida isolates 91.6% were susceptible to tested polyenes and 32.9% to all azoles. Less susceptible to polyenes isolates were noted in low percentage (0.7 to 4.2%) and to azoles more frequently (32.9 to 41.2%). Candida isolates resistant to antifungal agents tested were dependent from the kind of clinical samples and species of fungi. Monitoring of the susceptibility to antifungal agents by ATB commercial test seems to be useful tool for therapeutic purposes.

Antifungal Agents↗
PubMed1999

[Own clinical observations of toxocara infections].

Toxocarosis clinical forms wers diagnosed according to Kraus et. al. (1995). There were three forms: 1) asymptomatic - marked by hypereosynophilia and ELISA positive serologic reaction, 2) minor - with cutaneous, pulmomary and pseudorheumatic lesions, 3) major - with hepatosplenomegaly and multifocal inflammatory lesions of organ of sight. Over the years of 1994-1997 in Infectious, Parasitic and Tropical Diseases clinic of the Voivodship Specialist Hospital of Lódź we found and treated 137 Toxocara canis cases. Among them 63 (46:0%) asymptomatic, 57 (42.6%) minor and 17 (12.4%) major forms were diagnosed. The disease was detected in 80 (58.4%) adults and 57 (41.6%) children. Seventy six patients lived in towns and 61 in country. Minor form patients had the symptoms as follows: skin allergy, large joints lesions, augmentation in lymph nodes. Radiology examinations revealed pulmonary lesions. Using ultrasonography there was found hepatosplenomegaly and changes echogenity in patients with major form. Biochemical tests showed elevation in hepatic enzymes activity. Lesions of organ of sight were multifocal and usually included uveitis, retinitis, inflammation of anterior chamber and inflammation of vitreous body.

Adult↗
PubMed1988

Selected epidemiological and clinical aspects of malaria in the material of the Institute of Maritime and Tropical Medicine in Gdynia.

Despite numerous endeavours to eradicate malaria remains a problem to be solved. This is reflected in high morbidity and mortality rates in endemic zones of this disease, and in the continually growing parasites resistance to the drugs applied within chemoprophylaxis and the treatment employed. In the compass of 1976-1987 a group of 20 thousand people, back from the tropics, was examined. In that number 415 having suffered from malaria while stay in the endemic zone of the disease, in 64 patients malaria was diagnosed in the course of the examinations. They were all subjected to the therapy in the IMTM. In several cases serious complications occurred. In the conclusions the authors point at the insufficient and inaccurate use of chemoprophylaxis the necessity of adopting individual procedure towards each patient and of considering the possibility of Plasmodium sp. infection in the people with the fever of the aetiology unknown, referring their stay in malarial regions.

Aminoquinolines↗
PubMedDate not supplied

Malaria as an occupational disease.

In Poland, cases of imported malaria are noted at present. In Polish citizens who work abroad, malaria is considered as an occupational disease. 95 cases of malaria in Polish citizens treated at the Clinic of the Institute of Maritime and Tropical Medicine in 1984-1993 were subjected to retrospective analysis, considering their occupational, epidemiological and clinical aspects as well as permanent sequelae of the disease. The most numerous groups among the patients examined were seafarers, fishermen, priests and missionaries. They were infected mostly in West Africa, during the first year of work. The majority of patients neglected chemoprophylaxis of malaria. In about 1/3 of patients, the resulting incapacity for work exceeded 1 month and more. In 7% of patients, 6 months after the treatment, permanent sequelae of the disease were observed: damage to the central nervous system, liver, kidneys and heart. The social and material costs of this invasive occupational disease were high. Malaria is an important health problem in Poles who work in endemic areas. Malaria prevention should be intensified.

Adult↗