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Biomedical subjects

A Koukoulas

Publications and source records attributed to A Koukoulas.

3 recordsLinked to original sources

Does passive leg raising increase cardiac performance? A study using Doppler echocardiography.

Passive leg raising is commonly used for the initial treatment of hypovolemic shock. However, there are many reports which have pointed out that it does not produce significant autotransfusion effect. We tried to evaluate the effects of passive leg raising on the cardiovascular performance in coronary artery disease patients in stable condition. We studied 31 patients of 51 +/- 10 years. Two M-mode echocardiographic and continuous wave Doppler studies of aortic flow were obtained. The first was performed while the patient was lying on the left side and the second after passive leg elevation. Left ventricular end-diastolic dimension increased by 0.40 +/- 0.82 cm (P = 0.007), fractional shortening by 2.5 +/- 6% (P = 0.01), peak aortic blood velocity by 5 +/- 14 cm/s (P = 0.02), and velocity time integral by 1.7 +/- 3.0 cm (P = 0.0007). From the above it is concluded that passive leg elevation really does increase preload, and consequently cardiac performance, by the classical Frank-Staring relationship in normovolemic coronary artery disease patients.

Coronary Disease↗

Effects of a preload increase on ventricular filling in coronary artery disease.

This study was conducted to investigate the effects of a preload increase on ventricular filling dynamics in 50 coronary artery disease patients both before and immediately after leg elevation. Mitral and tricuspid peak E and A velocities and the mitral E/A velocity ratio increased after leg elevation whereas isovolumic relaxation time and mitral deceleration time decreased. The increase in tricuspid peak A velocity after leg elevation was related to the positivity of the exercise stress test (p = 0.01). The increase in mitral peak A velocity was related to the history of old myocardial infarction (p = 0.006).

Adult↗