PubMed Health⌕ Search

Biomedical subjects

A Krakowski

Publications and source records attributed to A Krakowski.

At least 19 recordsLinked to original sources
PubMed1992

Intertriginous drug eruption.

Presented are two patients who developed an unusual, and as yet unreported eruption due to amoxycillin. They exhibited an eruption confined to the intertriginous areas, which mimicked intertrigo. Although drug eruption can mimic a variety of idiopathic skin diseases, intertrigo is easily distinguished from drug eruption and has not been mentioned in the differential diagnosis of this reaction. It is suggested that drug reactions should be considered in the differential diagnosis of intertrigo, in particular of atypical and therapy-resistant cases. Early detection of these cases has practical importance since the elimination of the causative drug is essential for therapy success. Case 2 showed a response of the toxic epidermal neurolysis (TEN) type, which could have been very severe and dangerous had the diagnosis not been made in an early stage before the development of generalized TEN.

Adult↗
PubMed1989

Atenolol-induced cutaneous vasculitis.

We present a case of cutaneous vasculitis apparently due to an adverse reaction to atenolol. The causal relationship between the drug and the eruption was based mainly on circumstantial evidence. It has been further strengthened by positive results of the indirect rat mast cell degranulation test. The number of published cases of reaction to atenolol is limited. Cutaneous vasculitis has, to the best of our knowledge, never been reported as an adverse reaction to atenolol, although it is not a rare side effect of other beta blocker drugs including propranolol and practolol. Atenolol should be added to the list of beta blocker medications that may produce cutaneous vasculitis.

Atenolol↗
PubMed1988

Variations in aquagenic pruritus and treatment alternatives.

We report our experience in the treatment of two patients with aquagenic pruritus of the elderly and two patients with aquagenic pruritus. Our findings confirm previous reports by others indicating that aquagenic pruritus is not one homogenous entity but rather is composed of two similar but distinct entities, each of which responds to a different treatment. Patients with aquagenic pruritus were helped by adding sodium bicarbonate to the bath water while patients with aquagenic pruritus of the elderly responded to emollients. It is suggested that aquagenic pruritus and aquagenic pruritus of the elderly are two similar but distinct entities. Separating these two entities provides the key to successful treatment, because each of them responds to a different treatment without crossover. This report is only the second report indicating the effectiveness of sodium bicarbonate baths in patients with aquagenic pruritus. It is clear that further examples are needed to confirm these findings.

Adult↗
PubMed1988

The hair follicle mites (Demodex spp.). Could they be vectors of pathogenic microorganisms?

The hair follicle mites Demodex folliculorum and D. brevis are the most common permanent ectoparasites of Man. Ordinarily they are harmless to their human host and appear to be of no medical significance. We present, however, an unusual finding regarding this mite, namely, that in a potassium hydroxide mount of a skin scraping from a mycotic plaque we found numerous Demodex mites containing inside them spores of Microsporum canis. This could mean that the putatively inoffensive Demodex has the potential to ingest various microorganisms that are found in its niche and transport them to other areas of the skin or possibly to other individuals.

Acari↗
PubMed1987

Atypical crusted scabies.

Five cases of an atypical form of crusted (or Norwegian) scabies are described. Three cases occurred in patients who suffered from a malignant tumor, and two additional cases occurred in mentally retarded and physically debilitated patients. These cases should draw attention to the possibility of a scabietic infestation whenever a widespread, scaly, itchy dermatosis develops in a debilitated immunosuppressed patient.

Adult↗
PubMed1987

Dorfman-Chanarin syndrome. A case report and a review.

Dorfman-Chanarin syndrome in two sisters of Jewish Iraqi origin is reported. This heritable disorder of the metabolism of neutral lipids was manifested by congenital ichthyosis, vacuoles in the leukocytes, and variable involvement of liver, muscle, central nervous system, and the auditory system. In two asymptomatic members of the family leukocyte vacuoles were found as the only sign of the syndrome. Clinical, pathologic, ultrastructural, and biochemical findings are described. Previous reported cases are reviewed.

Adult↗
PubMed1987

Quinidine-induced lichenoid and eczematous photodermatitis.

We report 6 cases of photodistributed rashes due to oral administration of quinidine: 4 cases with a lichen-planus-like eruption and 2 with an eczematous dermatitis. The casual relationship between the drug and the eruption was established mainly by means of circumstantial evidence. It was further strengthened by an in vitro challenge test in 4 cases and by a rechallenge in 2 patients. The in vitro challenge test used was the macrophage migration inhibition test, which can be of diagnostic aid whenever a rechallenge of the patient is contraindicated. Quinidine-induced lichenoid eruption in a photodistribution seems to be more common than previously reported. Physicians should be aware of this type of drug eruption.

Administration, Oral↗
PubMed1987

Psoriasiform eruption induced by captopril and chlorthalidone.

We present findings from two patients who experienced a psoriasiform eruption apparently due to captopril and chlorthalidone. These drugs should be added to the growing list of drugs that may produce a psoriasiform eruption. Drugs other than beta-adrenergic blocking agents should be considered in the differential diagnosis of a psoriasiform drug eruption.

Aged↗
PubMed1987

[Norwegian scabies. Report of 2 cases].

Two cases with an atypical form of Norwegian (or crusted) scabies are presented. It is suggested that a systemic (first case) or a local (second case) alteration of the immune system paved the way for the development of this atypical presentation.

Adult↗
PubMed1986

Tinea capitis among children of Ethiopian immigrants.

The incidence, clinical appearance and causative agent of tinea capitis among children of Ethiopian immigrants, was studied. Out of 124 children examined, 36 had scalp lesions and 32 cases were confirmed as scalp-ringworm on direct microscopy. Culture showed the dermatophyte to be Trichophyton violaceum. The clinical presentation, resembling seborrheic dermatitis, without clinically apparent hair invasion, was atypical.

Child↗
PubMed1984

Immunofluorescence in cutaneous leishmaniasis.

A case of acute cutaneous leishmaniasis is reported in which skin biopsy of the lesion revealed deposits of IgM, fibrinogen and C3 in the blood vessel wall and granular deposits of IgG and C3 at the dermoepidermal junction. No immune complexes were detected in the healthy unaffected skin in the same patient and no circulating immune complexes were found in the blood. This case demonstrates tissue-bound immune complexes in cutaneous leishmaniasis.

Acute Disease↗