PubMed Health⌕ Search

Biomedical subjects

A Kreiger

Publications and source records attributed to A Kreiger.

8 recordsLinked to original sources

Clonidine as an adjuvant to local anaesthetic axillary brachial plexus block: a randomized, controlled study.

BACKGROUND: We compared the effects of clonidine added to levobupivacaine and bupivacaine on axillary brachial plexus block as well as the effectiveness of levobupivacaine alone compared with bupivacaine alone. METHODS: In this prospective, randomized, controlled, double-blind trial, four groups of 20 patients each were investigated, using (i) 40 ml of levobupivacaine 0.5% plus 0.150 mg of clonidine, (ii) 40 ml of levobupivacaine 0.5% plus 1 ml of NaCl 0.9%, (iii) 40 ml of bupivacaine 0.5% plus 0.150 mg of clonidine, and (iv) 40 ml of bupivacaine 0.5% plus 1 ml of NaCl 0.9%, respectively. The onset of motor and sensory block and duration of sensory block were recorded. RESULTS: There was no significant difference in duration between groups, but a significantly higher variance (P<0.001) was found in the two groups with clonidine than in the two groups without. CONCLUSIONS: These findings suggest responder and non-responder behaviour is a result of the addition of clonidine.

Adjuvants, Anesthesia↗

A light and electron microscopic study of the healing of pars plana incisions in the rhesus monkey.

Pars plana incisions were made in 11 rhesus monkey eyes. Six animals had injections of 0.1 ml of blood into the vitreous cavity with a 25-gauge needle and five animals had vitrectomy through a 4-mm incision with a multifunction vitrectomy probe. Six to 13 years later the scars in the pars plana were found to consist of fibrous tissue and blood vessels which extended from the episclera into the vitreous. The intravitreous scar was shaped by the incarceration of vitreous strands in the internal aspect of the wounds. There were quantitative, but no qualitative differences between the two types of incision. The ultrastructural features were those of mature scar tissue: fibroblasts, adult collagen, uveal melanocytes, macrophages, myelinated and non-myelinated nerves, and capillaries with non-fenestrated endothelium. There were associated proliferative ciliary epithelial changes, but no evidence of ciliary epithelial metaplasia.

Animals↗

Topical indomethacin in the treatment of chronic cystoid macular edema.

Eighty percent of 30 eyes with chronic cystoid macular edema (CME) after cataract extraction achieved improved visual acuity of three or more lines when treated with 1% indomethacin eye drops. Of these patients 53% demonstrated an "on/off" phenomenon induced by the initiation and cessation of treatment documented by visual acuity measurements and fluorescein angiography. This "on/off" phenomenon suggests that there is a direct relationship between the use of 1% indomethacin eye drops and the resolution of chronic CME after cataract extraction. Previous studies on the treatment of CME with indomethacin have not addressed the use of indomethacin eye drops for chronic CME.

Administration, Topical↗

[Vibration, a new way of cutting in ophthalmic surgery (author's transl)].

Rapid movement (vibration) of a movable scissor blade against a stationary blade at alternating current frequency (50 Hz) provides considerable improvement of cutting power and decreases distortion and crushing of the tissue. The article describes vibrational scissors for cataract surgery.

Cataract Extraction↗