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Biomedical subjects

A Krishna

Publications and source records attributed to A Krishna.

At least 73 records · Page 4Linked to original sources
PubMed1993

Morphological changes of the rete system in the ovaries of adult bat, Scotophilus heathi, during breeding cycle.

The present study describes a well developed rete ovarii in the ovary of the adult Indian vespertilionid bat, Scotophilus heathi, and supports the role of the rete system in early follicular growth in the ovary. A close contacts between the rete tubules and follicles have been found at the beginning of the follicular growth in the mature ovary. Ultrastructural features of connecting rete cells indicate the active protein synthesis, while those of intraovarian rete cells suggest their role in transportation of secretory materials.

Animals↗
PubMed1993

Chloramphenicol resistant enteric fever.

In recent times there have been several reports of chloramphenicol resistant enteric fever necessitating the use of other antimicrobial agents. Clinical profile of 15 chloramphenicol resistant patients of enteric fever was studied. Three such patients (20%) responded to chloramphenicol despite in vitro resistance to the drug. Hence chloramphenicol still remains the drug of first choice in enteric fever as a majority (68.4%--26 out of 38) of our bacteriologically proven enteric fever patients were cured by the drug. The remaining 12 cases responded satisfactorily to ciprofloxacin (46.7%), gentamicin (20%), and ofloxacin (13.3%). There was an increased incidence of complications among the 15 drug resistant cases as compared to 23 cases of chloramphenicol sensitive enteric fever observed during the same period.

Adolescent↗
PubMed1992

Pyogenic liver abscess causing acute Budd-Chiari syndrome.

Acute Budd-Chiari syndrome caused by compression of the inferior vena cava by a space-occupying lesion in the liver is rare in children. We report a case where the compression was due to a large staphylococcal abscess in the right lobe of the liver. A high index of suspicion in such a case ensures early intervention and saves life.

Acute Disease↗
PubMed1992

Effects of hCG and PMSG on responsiveness of ovary during period of delayed ovulation in an Indian vespertilionid bat, Scotophilus heathi.

Both hCG and PMSG treatments given either individually or sequentially between September and early February failed to induce ovulation in S. heathi, though they produced high degree of ovarian stimulation. The treatments induced ovarian enlargement, intense hyperaemia, marked changes in interstitial cells (ICs) and development of several antral follicles and varying degrees of abnormality in oocyte of most of the antral follicles. The percentage of abnormal oocytes in the ovary following hCG or PMSG treatment was dose-dependent.

Animals↗
PubMed1992

[The olfactory region of the bat Scotophilus heathi. Light and electron microscopic studies].

The present investigation reports light and electron microscopical aspects of the main olfactory epithelium (MOE) of the insectivorous bat Scotophilus heathi. Serial frontal sections of the nose and associated structures reveal: 1) that the MOE is located on most of the ethmoturbinals and on the proximal upper portion of the nasal septum; and 2) that the vomeronasal organ is absent in this species. The ultrastructure of the MOE of Scotophilus heathi is similar to that observed in other vertebrates. Moreover, we did not observe significant morphological differences between the MOE of male and female animals. Nevertheless, the supra-nuclear region of the supporting cells of males and females shows a different amount and distribution of "lysosome-like" cell organelles at the two times of the year investigated.

Animals↗
PubMed1991

Compartmentalized mast cell degranulations in the ovarian hilum, fat pad, bursa and blood vessel regions of the cyclic hamster: relationships to ovarian histamine and blood flow.

Ovaries from hamsters on each day of the oestrous cycle at 09.00 h were observed for the number of mast cells, the pattern of mast cell degranulation, histamine concentration and blood flow. On day 4 (pro-oestrus), ovaries were also observed at 9.00, 15.00 and 21.00 h. Mast cell degranulation was evaluated by 3 criteria: (1) no degranulation = less than 5 granules dispersed from the cell; (2) moderate degranulation = 5 or more granules dispersed but less than 15, and (3) extensive degranulation = 15 or more granules released. Blood flow was determined using radio-active microspheres in anaesthetized animals. Mast cells were observed in fat pad (beyond 2 mm of the bursal mesothelium), bursa (within 2 mm of the bursal mesothelium), hilum and near ovarian blood vessels (these 4 regions are collectively called the ovarian complex). The distribution of ovarian mast cells was not uniform. Most mast cells were near ovarian blood vessels (42.2%) and in the fat pad (37.2%). A moderate number of cells were in the bursal wall (20%) and only a few cells were observed in the hilum (0.64%). Mast cell number remained unchanged on days 1-4 of the cycle in each ovarian compartment. However, summation of the number of mast cells in the entire ovarian complex revealed a significant decline in number at 15.00 h on pro-oestrus. Alterations in mast cell degranulation were primarily restricted to 2 periods of the cycle (pro-oestrus and di-oestrus). An increase in moderate but not extensive degranulation was observed in only the fat pad and bursa on day 2 when compared with day 1 values. In most ovarian compartments on pro-oestrus, degranulation was higher than on any other day of the cycle. At 15.00 h on pro-oestrus, extensive degranulation in bursa, fat pad and blood vessel regions (but not hilum) coincided with an increase in ovarian histamine and decline in number of mast cells; ovarian blood flow also increased at the time but remained unchanged the remainder of the cycle.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗
PubMed1989

Multicystic kidney in association with hepatoblastoma--a case report.

In the absence of functional renal tissue on the right side, differentiating between a liver tumor and a renal tumor, both clinically and on routine imaging, is difficult. This clinical dilemma is highlighted here in a case report of a 2 year old girl with hepatoblastoma occurring in association with multicystic kidney. To our knowledge no other such case has been reported so far.

Carcinoma, Hepatocellular↗
PubMed1989

Histamine, mast cells and ovarian function.

Mast cells, endothelial cells, basophils and platelets are potential sources of histamine in the ovary. Little is known about the role of the latter three cell types in ovarian function. Several studies have revealed changes in the number and degranulation (release of histamine) of mast cells in the ovary during the cycle. Mast cells degranulate on pro-oestrus in the rodent ovary, and mast cells numbers increase in the theca externa of the dominant follicle in the bovine ovary. In rodents, mast cells are limited to the ovarian hilum and are not observed in follicles, corpora lutea and interstitium; this contrasts with larger species such as man, cows and monkeys where mast cells are observed throughout the ovary. Evidence is accumulating that mast cell degranulation in the ovary may be regulated by neuronal input. Neurones have been shown to have close morphological relationships with mast cells in the ovary. Histamine participates in regulating capillary permeability and blood flow in the ovary. These actions are induced by injections of LH, yet the mechanism by which LH induces mast cell degranulation is unknown. Histamine stimulates ovarian contractility, ovulation and follicular progesterone secretion in vitro. Whether these actions of histamine occur in vivo are currently unknown. This review gives a chronological description of the discoveries of the effects of histamine on ovarian function and makes suggestions for future research in this area.

Animals↗
PubMed1989

Intracellular detection of albumin in the ovaries of golden hamsters by light and electron microscopy.

Ovaries were obtained from golden hamsters during proestrus and immersion-fixed for the immunocytochemical localization of albumin by the peroxidase-antiperoxidase method. Another group of ovaries were obtained from immature perfusion-fixed animals which had been stimulated for 48 or 96 h by gonadotrophins. Perfusion-fixed tissues were processed for the ultrastructural albumin localization using the protein A-gold technique. At the light microscopical level, albumin positive cells were seen more often in the corona radiata and the inner layer of the granulosa, but seldom in the outer layer. Thecal and interstitial gland cells revealed albumin reactivity as did the intra- and extravascular spaces. Using the electron microscope, enriched gold grains signalizing a positive albumin response were detected over lipid droplets of granulosal, thecal and luteal cells. Though labeled coated vesicles were absent, the following functional significance is proposed for this study: precursors of steroidogenesis or steroids may be transferred as ligands of albumin into or within the cell after a receptor-mediated uptake of the albumin ligand complex.

Albumins↗
PubMed1988

Pulmonary blastoma in a neonate.

A rare case of pulmonary blastoma in a neonate is reported. Only one other neonate has been documented in the available English literature. The treatment consisted of surgical excision only.

Female↗