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Biomedical subjects

A Krohn

Publications and source records attributed to A Krohn.

13 recordsLinked to original sources

Radiographic findings in osteoarthritis of the knee joint are not correlated with cartilage histomorphology or immunohistochemistry.

The purpose of this study was to investigate whether radiographic joint space narrowing (JSN) of the lateral knee compartment predicts the histomorphological or immunhistochemical grading in cases of osteoarthritis of the knee joint. The lateral joint space was measured on weight-bearing radiographs. Femoral osteochondral plugs of 29 patients undergoing total knee replacement were obtained from lateral condyles. All these patients had severe osteoarthritis of the medial compartment, with the lateral compartment showing different stages of osteoarthritis. The specimens were histomorphologically evaluated with the Mankin score, and the expression of the cartilage-degrading enzymes MMP1 and MMP3 was measured. There was no correlation between the joint space and histomorphological or immunohistochemical data, whereas the enzyme expression was correlated with histomorphological grading. We conclude that radiographic assessment alone is not sufficient to evaluate the cartilage damage of the lateral condyle.

Arthroplasty, Replacement, Knee↗

[Studies on the mobility of soft tissue marks of the lower face].

The mobility of soft tissue points used for measuring the rest vertical dimension was assessed in 29 probands with full dentitions and 24 edentulous subjects. A video-aided procedure was used for recording the measuring pictures. Similar results were obtained with fully dentulous and edentulous subjects. For the upper jaw the point of the nose was the mark undergoing the least fluctuations, due to the action of the mimic muscles. For the lower jaw the least mobile skin area was between the labiomental sulcus and the gnathion.

Adult↗

The nature of the Oedipus complex in the Dora case.

In this paper we sought to study, through a detailed review of Dora's analytic material, the specific nature of her oedipal conflict and its expression in her treatment with Freud as manifested in her dreams, associations, and transference. We found that while Freud was surely correct in considering Dora's positive oedipal conflict as an important source of her psychopathology, the implication of her early regression to a phallic-oedipal position was not fully appreciated or interpreted, leading to her eventual premature termination. While Freud analyzed, largely following the end of the treatment, Dora's erotic love for Frau K., he did not see this love as deriving from an integrated phallic-oedipal complex which included competitive and castrative strivings toward men as well as wishes to love a woman from a phallic position. Thus we sought to extend Freud's analysis of the case by delineating the specific form of Dora's homosexual love, the genetic sources for it, and the aggressive wish toward men as they derive from a particular substage of the oedipal phase for females, the phallic-oedipal phase. We conclude that Dora's hostility toward Freud, her father and Herr. K. resulted not only from injured pride but, more basically, from her jealousy and rivalry with father for mother's love. In her treatment Dora's phallic-oedipal wishes became increasingly dominant. They were manifested in the transference with her first acting to engage Freud's interest and then thwarting his interpretive efforts, ultimately by leaving the treatment altogether. The case well illustrates the importance of understanding the role of the phallic-oedipal phase in female hysterical patients.

Adolescent↗

Psychological effects of symptoms associated with labyrinthitis. a case study.

The psychological effects of postviral labyrinthitis in a patient who had been undergoing intensive psychotherapy are reported. The mildness of the physiological symptome was in contrast to the magnitude of the psychological consequences. The general psychological effects of illness on the patient are differentiated from the specific psychological correlates of vertiginous symptoms. The factors that contributed to the psychological effects and the psychological impact of these symptoms are discussed. There is a special potency to the cited effects in patients with specific personality characteristics.

Adjustment Disorders↗

Some clinical manifestations of structural defects in a borderline personality.

A case is presented that illustrates specific clinical manifestations of structural deficits and psychopathological complexes characteristic of borderline patients. Following an overview of the patient's presenting problems and history, the patient's personality organization is conceptualized metapsychologically. Then the clinical manifestations of three core problem areas in the patient are explored: (1) deficits in narcissistic cathexis leading to clinically apparent, primitive, self-confirming character traits, (2) fear of helplessness and pathological attempts to establish a sense of control, and (3) arrest of drive development coupled with limited ego capacity for sublimation.

Adult↗