Application of the coupled harmonic oscillators model to the description of beta-cells of the pancreatic langerhans islets.
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Biomedical subjects
Publications and source records attributed to A Kukwa.
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Removing of focus cancer in partial laryngectomy is going with the risk of local recurrence and the appearances of the next atypia cancer focus in the respiratory tract. Using of the new endoscopic methods can allow for total control in out patient department.
The neck cysts are the most common congenital malformation in the head and neck area. In these cases the diagnosis is established on clinical examination, the results of USG and the aspiration biopsy. The problem of malignancy was very rare, but nowadays there is much more in literature about these. The criteria of cancer diagnosis in the neck cysts metaplasia of ephitelium are mentioned. In the ENT Department in Warsaw between September 1989 until December 1994 were treated 29 patients with the neck cyst. Four of them had diagnosed as cancer in histopathological examination. Improvement of some non-invasive technique let us to use them more extensive, especially USG. The examination can be repeated many times, especially in cases when the primary neck tumor was treated using conservative methods.
This study is a review of 69 patients with tumours in the parotid glands who underwent diagnosis and surgery, at the ORL Clinic in Warsaw during the years 1990-1994. 20% of all tumours were malignant; the dominant type in this group was mucoepidermale carcinoma. Pleomorphic adenomas were the most common benign tumours. The role of thin needle aspiration biopsy in diagnosis of parotid tumours was performed. In 85%, of cases the results were confirmed by histopathology. Methods and results of treatment are presented.
Papilloma of the nose requires radical, surgical procedure, because may occur of the recurrences and metaplasia. The lateral rhinotomy is the most recommended technique as good total and radical for excision of the tumor. We present 25 cases of papilloma treated in the Otolaryngological Department in Warsaw. The new methods of the pre-, intra- and post-operative evaluation using endoscopy, especially microscope endoscopy has been used. Endoscopy is also very valid methods for post-operative monitoring follow-up.
Partial laryngectomy of larynx cancer are limited by difficulties in reconstruction at the same time the anatomical way of the upper respiratory tract with secure maintenances defence and phonation functions. Authors present their own way of reconstructive surgery which can allow to make good condition for the comfortable life.
We present 45 patients with laryngeal carcinoma after partial various type laryngectomy results in 1989-1995. Frequency occurrence complication was dependent on localisation and expations. The most often complications after operation are; dyspnea which needs tracheotomy done and nor radicality in histopathological example which press the surgeon to make total laryngectomy. Authors present the types of conservative and surgical treatment of anatomical and functional reconstruction of larynx.
Authors present the case of carcinoma adenoides cysticum, which was located in small salivary glands of palatum. After surgical treatment and radiotherapy during 3 years observation of the patient two new ca adenoides cysticum focus were noticed. It can give evidence of cancer multifocus of cancer recurrents.
Twenty-three patients with facial nerve paralysis following surgery for a cerebellopontine angle tumour had a facial-hypoglossal anastomosis and simultaneous anastomosis of the cervical ansa with the distal stump of the hypoglossal nerve. In 18 patients, simultaneously with the neural anastomoses, additional transpositions of the temporalis and masseter muscles were performed. At follow-up examination 3-87 months after reconstructive surgery, eight patients had House grade II, ten grade III and five grade IV outcome. The EMG evidence of reinnervation was observed 5-11 months after anastomosis. Combination of the facial-hypoglossal anastomosis with simultaneous myoplasty and with anastomosis of the distal hypoglossal nerve stump to the ansa cervicalis provides the advantage of immediate protection against ophthalmic complications, prevents hemiatrophy of the tongue and gives good functional results when reinnervation of the facial muscles takes place.
Experiments were performed with anaesthetized (urethan and chloralose) spontaneously breathing rabbits. Horseradish peroxidase (HRP) was injected (1 mg) with a Hamilton syringe into the end of the sectioned mylohyoid nerve. The HRP-labelled neurones could be localized in the motor nucleus of the trigeminal nerve (N.V.mt.). It was found that the labelled neurones are present in the caudal and intermediate part of the nucleus. However, their largest agglomerations were noted in the caudal part, where they occupied the entire frontal section of the nucleus. It is assumed that the N.V.mt. directing their axons to the muscles of the upper respiratory airways, simultaneously send collaterals to the central respiratory neurones participating in the regulation of the respiratory rhythm. According to this hypothesis the neurones of the N.V.mt. may ensure synchronisation between the upper and lower respiratory system.
Authors described the technique of surgical treatment of the longstanding, irreversible peripheral facial palsy. Both neurography and myoplasty were combined. The most functionally effective detail in this method is the substitution of the hypoglossal nerve function with the descending branch of the cervical ansa.
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Authors described the scheme of the functional reconstruction of the face in patients with protracted, irreversible, peripheral facial palsy and the subsequent rehabilitation. A new, own method of treatment has been introduced considering anatomical and functional relations.
The authors describe various grades of middle ear malformations in 22 patients with developmental defects of the first and the second branchial arch. Middle ear malformations were divided into three groups, according to Altmann's classification, on the basis of physical examination, X-ray investigations and surgeon's opinion. The analysis of the material helps in the assessment of possible anatomical and physiological benefits of surgery in each group of malformations.
The effects of ketamine on the activities of the mylohyoid nerve (a branch of the Vth nerve) and of both phrenic nerves were investigated in rabbits anaesthetized with halothane, paralyzed and artificially ventilated. Intravenous administration of ketamine elicited a marked prolongation of the phrenic inspiratory discharge (without significantly affecting its amplitude) and a depression of the mylohyoid expiratory activity. An elimination of the volume-related input from the lungs ("no-inflation manoeuvre") or deflation elicited under these conditions typical apneustic pattern of breathing. The response to tracheal occlusion at peak-inspiration was "classical". We conclude that ketamine inhibits the Vth nerve motor nucleus which is not only an important component of the central inspiratory-inhibitory neurones but also a "relay station" between the vagal and the central inspiratory "off-switch" mechanisms.
Some profoundly deafened patients, who cannot be helped by sound amplification, claim to perceive auditory sensations when alternating currents up to 100 Hz are passed through electrodes applied to the skin of the external ear canal. A portable speech processor has been developed which supplies this current. The signal is a balanced square wave, the frequency of which is proportional to the first formant frequency. The amplitude is proportional to the intensity of voiced sounds. In order to fit the narrow frequency and dynamic range of the electrical stimulus, the speech processor produces a downward frequency transposition and strong limitation of the dynamic range. The device has been tested for (1) discrimination of environmental sounds; (2) question/statement discrimination; (3) identification of vowels and consonants in vowel/consonant/vowel context; (4) lip-reading with and without the prosthesis.
The authors described the clinical signs and consequences of suffocations during sleep apnea. They presented the results of the surgical intervention of nasal obstruction in patients with sleep apnea. The during-all-night examinations of these patients proved the possibility of positive effects of surgical intervention of nasal obstruction in patients with sleep apnea.
A detailed cephalometric analysis was conducted on lateral x-rays from 30 adult patients with obstructive sleep apnea (OSA) and 12 age- and sex-matched controls. Statistical findings show that OSA patients are different from controls in at least five ways: 1. Their tongue and soft palate are significantly enlarged. 2. The hyoid bone is displaced inferiorly. 3. The mandible is normal in size and position (no micrognathia or malocclusion), but the face is elongated by an inferior displacement of the mandibular body. 4. The maxilla is retropositioned and the hard palate elongated. 5. The nasopharynx is normal, but the oropharyngeal and hypopharyngeal airway is reduced in area by an average of 25%, a factor that could produce or enhance OSA symptoms. These data suggest that cephalometric evaluation could be useful when used with head and neck examination, polysomnographic and endoscopic studies to evaluate OSA patients, and to assist with the planning/surgical treatment for improvement of upper airway patency.