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Biomedical subjects

A Kukwa

Publications and source records attributed to A Kukwa.

At least 55 records · Page 3Linked to original sources
PubMed1985

Influence of vagal input on cerebral blood flow in monkeys and dogs after experimental cerebral vasospasm.

Cerebral blood flow (CBF) was a response to experimental subarachnoid haemorrhage (SAH) in four monkeys ,and three dogs. Decrease in CBF was observed in the white and gray matter and in the flow measured within the internal carotid artery as the result of SAH. Bilateral vagotomy enhanced CBF in the gray matter and blood flow in the internal carotid artery to values exceeding the control ones. Results suggest the existence of a receptor susceptible to subarachnoid haemorrhage and connected with vagal nuclei.

Animals↗
PubMed1983

Decrease of mast cells in the stroma of human cancer.

The number of mast cells in the stroma of human squamous cell cancer -- keratoblastif cum, paraepidermale and male diffusa was 2-30 times lower than in the stroma o-normal squamous epithelium or in the connective tissue distant from neoplastic epithelium. These differences are statistically highly significant. The reduction of mast cel, number apparently might be the result of exhaustion of heparin-containing granules which interfere with tumor growth.

Aged↗
PubMed1979

Cellular immunity in patients with epidermoid cancer of the head and neck.

Forty-three patients with squamous cell carcinoma of the head and neck were evaluated immunologically at various times before and after treatment. Impaired DNCB skin reactivity was found in patients with more advanced disease (Stages II-IV). In the 24 patients evaluated prior to therapy, only the mean percentages of two subpopulation T-cell tests, T-RFC29 and "active" T-RFC and mean absolute T-RFC29 per mm3 and PHA responses were significantly depressed. These depressed values could not, however, be correlated with the stage of the disease. In patients with poorly to moderatley differentiated tumors there was a significant decrease in mean percentage of active T-RFC and PHA stimulation. A marked difference in mean percentages of T-RFC29 between pretreated patients without nodal involvement (40.5 +/- 2.1) and those with this complicity (58.1 +/- 4.9) suggests that this assay may be used to detect occult nodal involvement. A comparison of the effects of surgery, irradiation and the combination of the two no patients indicated that only radiation affected any of their immune parameters. Irradiated patients demonstrated a marked decline in the mean absolute level of lymphocytes, total T-RFC and mean PHA responsiveness within one month of the termination of therapy: however, these values returned to the pretreatment level within seven months. None of the treatments was effective in "curing" the immune deficits observed in pretreatment patients.

B-Lymphocytes↗