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A Kumasawa

Publications and source records attributed to A Kumasawa.

6 recordsLinked to original sources
PubMed1986

Mathematical analysis of transport phenomenon to the blood from the site of intramuscular injection with ampicillin in the rat.

The mathematical formula with time function of transport phenomenon is obtained by the analysis of the concentrations of ampicillin in the serum, bile and urine. This formula indicates the speed of transport of the drug, or the ratio of the vascular permeability of it for the administrated dose from the site of intramuscular injection into the blood as the time function. About 80% of ampicillin was transported into the blood through capillaries for 120 min from the beginning of intramuscular injection.

Ampicillin↗
PubMed1983

[Primary lung cancer treated with fast neutron].

Forty-nine patients with primary lung cancer were treated with fast neutron (average energy, 6 MeV) by so-called mixed therapy method at the Institute of Medical Science, University of Tokyo. Control group (Linacx-ray, 10 MV) was not randomized one, however, these patients were treated by the same chief radiotherapist (Dr. Iino) at Shizuoka Prefectural Hospital and its interval was almost the same to neutron group. The crude survival rate did not show any significant difference between them except for 1 year survival of Stage II (p less than 0.05). Radiation pneumonitis and tumor regression were thought to be almost the same. The incidence of pneumothorax (3/49) was somewhat higher than the x-ray group (3/119) but there was no significant difference. We are now planning a new mixed therapy method which has short time interval (less than 3 hours) between neutron and x-ray irradiation in expectation of decrease of shoulder in x-ray surviving fraction curve.

Fast Neutrons↗