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Biomedical subjects

A Kursbaum

Publications and source records attributed to A Kursbaum.

5 recordsLinked to original sources
PubMed1990

[Acute hepatitis and pneumonitis associated with nitrofurantoin].

Nitrofurantoin is widely used in the prophylaxis and treatment of urinary tract infections. Most untoward side-effects are mild and due to gastrointestinal intolerance. More severe side-effects consist of acute and chronic pulmonary reactions, liver damage, blood dyscrasias and peripheral neuropathy. Nitrofurantoin is a rare cause of hepatic injury, with a spectrum of toxic reactions ranging from acute, self-limited, hepatocellular or cholestatic injury to chronic active hepatitis. We present a case of acute hepatic injury and pneumonitis related to nitrofurantoin. When this drug is given periodic clinical and laboratory monitoring is important.

Acute Disease↗
PubMed1977

Hypertension due to Ask-Upmark kidney.

A young girl in whom severe hypertension was cured by the surgical removal of a unilateral hypoplastic kidney (Ask-Upmark kidney) is described. The clinicopathological features of the Ask-Upmark kidney are described with particular reference to the aetiology of the hypertension as well as the selection of patients for surgery. No abnormality of the renin-angiotensin system was detected.

Adolescent↗
PubMed1976

Anti-heart autoantibodies in ischaemic heart disease patients.

One hundred and ninety-nine ischaemic heart disease (IHD) patients were studied with regard to the prevalence of anti-heart autoantibodies (AHA). The incidence of AHA in IHD patients was 1%: one out of 102 patients who suffered acute myocardial infarction (AMI), one out of seventy-two patients who suffered from acute coronary insufficiency (ACI), and none out of twenty-five patients with other signs and symptoms of IHD, had AHA in their sera. An additional 2% of patients who suffered from AMI developed detectable antibody levels during a follow-up period of 15 days. In comparison,, 53% of patients (eight out of fifteen) who underwent heart surgery and who had no AHA prior to operation, developed these antibodies in their sera during 1-2 weeks following operation.

Adult↗