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Biomedical subjects

A Kyriakidis

Publications and source records attributed to A Kyriakidis.

At least 19 recordsLinked to original sources
PubMed2006

The effectiveness of reinfusion after total knee replacement. A prospective randomised controlled study.

The purpose of our study was to determine the effectiveness of a postoperative autologous blood reinfusion system as an alternative to homologous, banked blood transfusions in total knee arthroplasty. We carried out a prospective randomised controlled study on 60 patients having unilateral total knee replacements. In all these patients, the same surgical team applied the same surgical technique, and all patients followed the same rehabilitation program. In 30 of these patients (group A), a reinfusion system of unwashed salvaged blood was applied, and they were supplemented postoperatively with banked blood transfusions when required. A control group of 30 patients (group B), in whom standard suction drains were used, received one unit of homologous banked blood transfusion intraoperatively and additional blood transfusions postoperatively when required. The administration of banked blood transfusion was determined by the haemoglobin value (<9 mg/dl) and/or clinical signs (blood pressure, pulse, etc.). The values of haemoglobin, haematocrit and platelets were recorded preoperatively and the first, fifth and 15th postoperative days, respectively. Five patients of group A required nine units of homologous blood (0.3 units/patient) postoperatively. Ten patients of group B required an additional 15 banked blood units postoperatively (in total 45 banked blood units for group B; 1.5 units/patient). In the study group, the total homologous blood requirements were reduced by 80%, while the postoperative blood requirements were reduced by 50%. There was no significant difference in the postoperative haematocrit and haemoglobin values between the two groups. The cost of the blood management in the study group was reduced by 36%. The use of an autologous blood reinfusion system reduces highly effectively the demands of homologous banked blood transfusion in total knee arthroplasty.

Aged↗
PubMed2003

Diameter of mammary terminal ducts as an additional tool in evaluation of women with polycystic ovarium disease.

OBJECTIVE: Aim of this study was to show the change of diameter of mammary ducts in relation to polycystic ovaries disease. DESIGN: Women who took part were divided into two groups- the first with polycystic ovaries disease and another second group with no such disease. METHOD: To both groups a series of laboratory, clinical and ultrasound (u/s) exams were used to diagnose polycystic ovaries disease. Furthermore u/s measurement of mammary ducts was used to define the diameter. RESULTS: In women with polycystic ovaries disease u/s showed an increase in diameter of mammary ducts whereas in the second group we didn't observe such finding. CONCLUSION: Our study showed that there seems to be a strong relation between the increased diameter of the main terminal lactiferous ducts- the polycystic configuration of the ovaries and the hormonal levels.

Adult↗
PubMed2001

Increased temperature of malignant urinary bladder tumors in vivo: the application of a new method based on a catheter technique.

PURPOSE: The aim of this study was to investigate the existence of any thermal difference between malignant tumors and inflammatory benign lesions of the human urinary bladder and to determine whether it correlates with tumor angiogenesis quantification. PATIENTS AND METHODS: A new method, developed in our institute, is introduced to detect temperature in human urinary bladder, in vivo. This method is based on a thermography catheter. We calculated the differences of the temperature of the solid tumor and of a normal area (Delta T) on 20 subjects (mean age, 72.5 years; 95% confidence interval [CI], 68.5 to 76.4). According to the biopsy histology, Eight (40%) patients had benign tumors, and 12 (60%) had malignant tumors. RESULTS: We found significant differences of Delta T between patients with benign and malignant tumor (P <.001). Also, differences were found for the mean values of angiogenesis level between malignant and benign tumors (P =.0261), and a moderated positive correlation was estimated between the degree of angiogenesis and Delta T (P =.02). Based on logistic regression analysis, we found that a 1-degree increase of Delta T triples the odds of a patient having a malignant tumor (odds ratio = 2.91; 95% CI, 1.97 to 7.78; P <.001), adjusted for the degree of angiogenesis (P =.0236) and the grade of tumor (P <.001). A threshold point of Delta T = 0.7 degrees C was determined, with sensitivity 83% and specificity 75%. CONCLUSION: These findings suggest that the calculated difference of temperature between normal tissue and neoplastic area could be a useful criterion in the diagnosis of malignancy in tumors of the human urinary bladder.

Aged↗
PubMed2001

Splenic artery aneurysm rupture.

BACKGROUND: Splenic artery aneurysms are uncommon even though they are second only to those of the aorto-iliac system. There is also controversy regarding their management. METHODS: We report the case of a 50-year-old patient with ruptured splenic artery aneurysm and review the literature regarding its diagnosis and management. RESULTS: The patient underwent emergency laparotomy and splenectomy was performed. CONCLUSION: Resuscitation and an aggressive surgical approach should be taken in order to save the life of the patients.

Aneurysm, Ruptured↗
PubMed1996

Prostatic tissue distal to the verumontanum and its significance for adenomatous recurrences after transurethral resection of the prostate. A cadaver study.

To elucidate possible causes of recurrences after transurethral resection of the prostate (TURP), we performed an anatomical study of the prostate in 37 cadavers. The anatomical study showed that a significant proportion of the prostatic adenoma laid below the verumontanum. This proportion in relation to the total prostatic length varied from 8.33 to 44.44%, while in relation to the weight it varied from 2.08 to 36.84%. After transurethral resection of the prostatic adenoma, part of the apical lobes below the verumontanum remains intact deliberately to secure continence. These adenomatous tissues left behind create the problem of the residual apical lobe. Recent reports in the literature have shown a higher incidence of prostatic adenomatous recurrences following TURP than after open prostatectomy. From our study and from an extended search in the literature, it seems that a possible reason for adenomatous recurrences can be due to the remaining residual apical lobes that are left behind after TURP, providing that the resection had been complete.

Humans↗
PubMed1995

Ureteral endometriosis in a female patient presenting with single-kidney anuria.

Endometriosis affecting the urinary tract is very rare. We report on a female patient with a single kidney who presented with anuria due to ureteral endometriosis. Initially a limited ureterectomy with an end-to-end anastomosis was performed. After removing the stent, endometriosis recurred. On reexploration, the terminal ureter was removed and the sound end reimplanted into the urinary bladder. A salpingo-oophorectomy was performed, and danazol 400 mg twice daily was started, with very satisfactory results. Endometriosis on a single acquired ureter causing anuria has, to our knowledge, not been reported previously. The modality of treatment is local excision, oophorectomy, and danazol.

Adult↗
PubMed1995

A clinical diagnosis of urinary bladder (extra-adrenal) phaeochromocytoma.

Urinary bladder (extra-adrenal) pheochromocytoma is a catecholamine-producing tumor that arises from chromaffin cells in the extra-adrenal paraganglion system of the urinary bladder. The symptoms and signs result from the release of epinephrine and/or non-epinephrine, which is more prominent during micturition. The most serious consequences of the disease are paroxysmal hypertension during micturition and malignant degeneration. Thus, proper treatment is mandatory.

Humans↗
PubMed1994

The potential for contamination of continuous spinal catheters.

The distal tip of 100 spinal catheters were cultured. They were obtained from 100 patients receiving continuous spinal anesthesia, 32 of whom underwent orthopedic surgery and 68 urologic surgery. The catheters remained in place 24 to 72 hours. Six of the catheters were found contaminated; five of the six were obtained from orthopedic patients and one of an urologic patient. There was a statistically significant difference between the duration of implantation and contamination, in the time span of 24 to 72 hours. There was no statistical significance between the duration of implantation and contamination neither in orthopedic nor in urologic patients. None of these catheters caused any clinical infection.

Aged↗
PubMed1983

X-ray diffractometric analysis of L-cystine stones in 12 patients.

In 12 of 21 cystinuric patients, the components of cystine stones, either previously passed or removed at surgery, were studied by X-ray diffractometry and chemical analysis. The results of diffractometry suggested that, in addition to cystine, the stones contained sodium urate and ammonium magnesium orthophosphate hydrate, although chemical analysis was negative for these components. The role of uric acid in cystinuria is discussed.

Cystine↗