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Biomedical subjects

A L Divonin

Publications and source records attributed to A L Divonin.

11 recordsLinked to original sources
PubMedDate not supplied

[Changes in the liver circulation and kidney function during pulsatile and non-pulsatile perfusion].

Pulsatile flow perfusion (PFP) requires smaller volume of additional infusion. Extravascular hyperhydration is more marked after nonpulsatile flow perfusion (NPFP). In NPFP there is an increase in free water clearance, lower urinary osmolality and diuresis rate. PFP prevents urinary hypoosmolality and retains baseline values of free water clearance. No significant differences in Na+ urinary excretion have been revealed. Bilirubinemia level following NPFP was significantly higher than the baseline level, while following PFP the level of total and bound bilirubin remained unchanged. No differences in the total hepatic flow have been observed during pulsatile and nonpulsatile flow perfusion.

Cardiac Surgical Procedures↗
PubMedDate not supplied

[Study of peripheral blood circulation during continuous and pulsatile perfusion based on the data of transcutaneous pO2 and pCO2 monitoring].

The study was performed on 22 patients with congenital heart valve defects after hypothermic cardiopulmonary bypass surgery. Transcutaneous and arterial pO2 and pCO2 have been measured at different stages of investigation. Nonpulsatile flow was applied to 10 patients and pulsatile flow--to 12 patients. Pulsatile pressure was maintained at about 30 mmHg. Transcutaneous index, carbon dioxide gradient and transcutaneous oxygen shunt have been calculated. Perfusion caused a decrease in transcutaneous pO2 and transcutaneous index, as well as an increase in transcutaneous O2 shunt. The use of non-pulsatile flow caused the most marked peripheral vasoconstriction. Transcutaneous index demonstrates that peripheral circulation decrease in pulsatile flow is 3 times lower than in non-pulsatile flow. Calculation of transcutaneous index and O2 shunt based on transcutaneous pO2 and pCO2 values can characterize peripheral circulation prior to, during and following perfusion.

Blood Circulation↗
PubMedDate not supplied

[Changes in hemodynamic indices during perfusion with pulsatile and steady currents in aortocoronary bypass surgery].

Hemodynamic parameters were compared in 28 patients with ischemic heart disease subject to cardiopulmonary bypass surgery with non-pulsatile (group 1) and pulsatile flow (group 2). Systolic, diastolic and mean blood pressure (MBP) was assessed, total peripheral vascular resistance (TPVR) was calculated, esophageal, rectal and skin temperature was measured. Volumetric perfusion rate was the same in both groups. Pulse pressure was maintained at the level of 35 mmHg. MBP at the stage of hypothermia plateau and during warming decreased in both groups. It was significantly lower in group 1 at the beginning of warming and during clamp relief from the aorta. At the end of cooling period TPVR was lower with the use of pulsatile than non-pulsatile flow. It increased drastically towards the end of hypothermia plateau in group 1. During clamp relief from the aorta TPVR values did not significantly differ from baseline in group 2 and remained high in group 1. The warming rate happened to be greater in pulsatile than in non-pulsatile flow.

Coronary Artery Bypass↗