PubMed Health⌕ Search

Biomedical subjects

A L Dudarev

Publications and source records attributed to A L Dudarev.

At least 19 recordsLinked to original sources
PubMed1992

Tumor marker CA 125 in diagnosis, monitoring management and follow-up of patients with ovarian tumors.

The concentration of CA 125 was defined in the blood serum of 151 patients with ovarian tumors: benign--49, borderline--5 and malignant--97. In 75.7% of benign tumors CA 125 concentrations did not exceed the normal level. In two from five patients with borderline tumors CA 125 concentration varied from 47 to 130 U/ml. High levels of CA 125 (from 125 to 10.000 U/ml and higher) were revealed in 54 from 57 patients (94.7%) with malignant ovarian tumors. If in Stages I and II elevated CA 125 levels (from 125 to 430 U/ml) were discovered in 71.4% and 80.0% of the cases, respectively, then in Stages III and IV CA 125 levels rose from 300 to 10.000 U/ml and higher in all cases. High CA 125 concentrations were noticed in 95.7% of patients with clinical signs of recurrences of the disease, and it was proved at "second-look" surgery. Thus, it was expedient to use CA 125 widely for an early detection of ovarian cancer, as a control on the efficiency of therapy and in diagnosis of subclinical recurrences of the disease.

Antigens, Tumor-Associated, Carbohydrate↗
PubMed1991

[Physicotechnical and dosimetric support of human whole-body irradiation in a standard medical source of photon radiation].

The paper is concerned with physicotechnical and dosimetric support of technology of therapeutic whole-body irradiation on a serial gamma apparatus ROKUS, with which a majority of radiological institutions in the USSR are fit out. Technology consists of the following procedures: patient positioning with relation to a source with a horizontal axis of radiation. Correction of dose distribution by means of a three-element compensator taking into account patient's constitutional peculiarities and preradiation preparation data; double irradiation in the bilateral regimen in the supine position.

Filtration↗
PubMed1991

[Gastric emptying rate in healthy subjects and patients (a radionuclide study)].

The authors proposed a method for the determination of differences in the rate of evacuation of 3 types of test breakfast: boiled semolina, boiled semolina with proteins or fat. Evacuatory function of the gastroduodenal system was investigated in healthy persons and in patients using a gamma-camera. The results obtained have shown that in a majority of healthy persons carbohydrate breakfast was evacuated at the highest rate, breakfast with egg protein was evacuated slower, and breakfast with butter was evacuated even much slower. In duodenal ulcer the rate of evacuation of all 3 types of breakfasts was slowed down, and evacuation was undifferentiated (all 3 types were evacuated at the same slow rate). In patients with liver cirrhosis the evacuation of carbohydrate and protein breakfasts was slow, in calculous cholecystitis these types of breakfasts differed slightly as a result of the slow evacuation of carbohydrate breakfast. The evacuation of breakfast with butter was inhibited almost to the same degree. These results indicate the complex nature of gastric content evacuatory disorders in gastroenterologic patients, and it should be taken into account in differential diagnosis and therapy.

Cholecystitis↗
PubMed1988

[Radionuclide study of liver function in polycythemia vera and other types of polycythemia].

Clinico-laboratory and radionuclide (radio-hepatography with 131I-rose bengal and liver scanning with 198Au colloid solution) investigation of liver function was performed in 110 patients with polycythemia vera during exacerbation, in 16 patients with symptomatic erythrocytosis (10--chronic pulmonary disease, 3--polycystic kidney, 2--obesity, 1--peptic ulcer), and in 11 patients with a polycythemic form of myelofibrosis. The results of the radionuclide method showed disturbed liver function in 51 (46.3%) patients with polycythemia, in 4 patients with myelofibrosis and in 3 with erythrocytosis which were characterized by a decrease in hepatocytic absorptive-excretory function and a decrease in the activity of the reticulo-histiocytic stroma. Liver changes depended on a stage of disease and were detected earlier than with the use of biochemical methods. As distinct from erythrocytes, one-type disorders were noted in the patients with myelofibrosis. Correlation in the lever of RP accumulation in the spleen, its sizes and stage of disease was established. Liver function returned to normal after cytostatic therapy in the patients with stage IIA polycythemia, partially IIB stage, during remission.

Adult↗
PubMed1983

[Radiotherapy in the prevention of postoperative and traumatic complications].

An analysis of the results of radiation therapy of 587 patients with postoperative and traumatic complications has shown that special gamma-therapy used at early time following trauma or surgical intervention, with the first clinical signs of an incipient inflammatory process (the so-called "anticipating" irradiation), makes it possible to avoid the development of serious postoperative, post-traumatic complications: wound suppuration, fistulas, secondary parotitis, postamputation pain syndrome, "needle" osteomyelitis, keloid cicatrix, skin graft rejection, etc. In the authors' opinion, this promising trend in radiotherapy of nontumorous diseases is worth a wider using in clinical practice.

Adolescent↗
PubMed1983

[Rate of gastric emptying after vagotomy in duodenal ulcer].

An analysis of results of studying the rate of emptying the stomach in 103 patients with duodenal ulcer has shown that evacuation was considerably quicker in patients in the vertical position than in those in horizontal position. It was slower in patients with subcompensated or decompensated stenosis. After vagotomy the emptying of the stomach took less time. In patients with a recurrent ulcer slower evacuation was noted but with the narrowing of the pyloroduodenal canal.

Adult↗