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Biomedical subjects

A L Kostiuchenko

Publications and source records attributed to A L Kostiuchenko.

104 records · Page 6Linked to original sources
PubMedDate not supplied

[Possibilities of management of dyspeptic symptoms in the immediate postoperative period].

Analysis of the postoperative course of 1276 patients has shown that the incidence of nausea and vomiting in the first hours after surgical intervention does not depend on the mode of analgesia. Dyspepsia in the immediate postoperative period occurred in more than 1/3 of the patients after surgery on the bile duct. Addition of metoclopramide or dimetpromide to premedication helped reduce the incidence of postoperative vomiting. An antiemetic drug should be an obligatory component of premedication.

Dyspepsia↗
PubMedDate not supplied

[The detoxifying function of the pulmonary parenchyma in patients with acute infectious lung destruction].

The study of arteriovenous ratio of medium-molecular oligopeptides level in 32 patients with acute infectious lung destructions has established an important detoxicating role of the lungs in endotoxemia syndrome during pulmonary-pleural suppurations. It has been found that, with the pronounced endotoxemia syndrome, during catabolic phase of the disease the lungs turn from toxin filter into their source. Detoxicating capacity of the lung parenchyma was shown to be more dependent on the severity of general metabolic disturbances than on the dissemination of suppurative lung destruction.

Acute Disease↗
PubMedDate not supplied

[New potentials for assessing the efficacy of extracorporeal blood correction methods in treating patients with acute suppurative destructive diseases of the lungs and pleura].

Integral mathematical analysis of changes in the peripheral blood formula was used in multiple-modality treatment of 19 patients with acute infectious destructions of the lungs and pleura. Extracorporeal methods of hemocorrection were used in the treatment. The leukocytic formula entropy, number of tension signs, degree of adaptation reaction, and leukocytic index of intoxication were assessed. Changes in the analyzed parameters were found to depend on the initial severity of patient's status, type of extracorporeal perfusion, and disease outcome. The authors came to a conclusion about the informative value of mathematical integral parameters which permit outlining the approaches to prediction of the disease outcome and plan individual treatment.

Acute Disease↗
PubMedDate not supplied

[Multiple organ failure syndrome in critically ill patients].

A new approach to defining the notion of multiple organ failure is proposed. It is based on division of the organ humoral injuries at the stages of dysfunction, insufficiency, and failure. Criteria of these stages are defined for the central nervous and cardiovascular systems, lungs, liver, kidneys, and gastrointestinal tract.

APACHE↗
PubMedDate not supplied

[Prospects of the use of caudal epidural anesthesia].

Caudal epidural anesthesia for interventions on the lower limbs and pelvic organs was used in 525 patients. A specific feature of the method is use of hypoosmolic local anesthetic solution (osmolality 260 mosmol/kg) containing lidocaine, 0.9% sodium chloride, and distilled water. Pathologic studies showed that in adult patients, at least 40 ml anesthetic should be injected into the caudal canal for adequate blocking. During surgery, caudal epidural anesthesia reliably protected from surgical trauma without side effects for respiration and circulation. The duration of analgesic effect was 3 +/- 0.5 h and even longer, if local anesthesia was potentiated with sedative drugs. No complications were observed, failures occurred in 5.2% cases. The method is simple and reliable and is recommended for practice.

Adolescent↗