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Biomedical subjects

A L Mehle

Publications and source records attributed to A L Mehle.

3 recordsLinked to original sources

Erythromelalgia.

Erythromelalgia, characterized by temperature-dependent redness, pain, and warmth in one or more extremities, may be a primary disease or occur secondarily to underlying illnesses. Myeloproliferative disorders (eg, essential thrombocythemia) and a number of other associations have been reported. Two cases are described: one associated with essential thrombocythemia and the other the first reported case associated with pernicious anemia.

Aged

Optimal use of an occlusive dressing to enhance healing. Effect of delayed application and early removal on wound healing.

We examined the effect of delayed application and early removal of a polyurethane dressing on excisional wounds in swine. Backs of pigs were wounded with an electrokeratome, and wounds were divided into the following treatment groups: (1) air exposed; (2) dressings applied immediately after wounding and kept on until wounds were evaluated; (3) dressings applied immediately after wounding and removed at 6, 24, or 48 hours; and (4) dressings applied 2, 6, and 24 hours after wounding. Wounds were excised on days 3 through 7 and incubated in sodium bromide to allow separation of the epidermis and dermis. Specimens were considered healed if no defect was present. To promote optimal resurfacing in superficial wounds, polyurethane dressings need to be applied within two hours after wounding and should be kept in place for at least a 24-hour period.

Animals