Biomedical subjects
Publications and source records attributed to A L Merlis.
Primary malignant melanoma arising from the leptomeninges is a rare entity. We describe the computed tomography findings and clinical course in two cases. The literature on this subject is briefly reviewed. An expanded differential diagnosis is presented for dural convexity tumors simulating the computed tomography appearance of meningiomas.
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The mother of a stillborn anencephalic child subsequently had twins with macrocephaly due to a cystic malformation of posterior brain structures, compatible with the Dandy-Walker syndrome.
Forty patients were studied by computerized tomography and by radionuclide brain imaging. The final diagnosis was infarction in 29 patients, intracerebral hematoma in seven, acute SAH in one, and old cerebrovascular accidents in three. CT was far superior to RN in detecting intracerebral hematomas and distinguishing them from cerebral infarction. The results of CT and RN tests were comparable regarding the percentage of abnormalities. However, the results in the same patients were not identical in 55% of the cases, indicating a complementary role for the two tests. There was no relationship between the frequency of abnormalities on CT and the time lapse after the onset of cerebral infarction. RN uptake was not seen in patients with old cerebrovascular accidents.