Experimental arteriosclerosis in dogs. Evaluation of anatomopathological findings.
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Animals↗
Biomedical subjects
A L Robertson
Publications and source records attributed to A L Robertson.
Effects of peripheral blood monocytes on human vascular cell proliferation.
Incubated human peripheral blood monocytes release a factor(s) which specifically stimulates homologous vascular smooth muscle (SMC) but not endothelial cells (EC) to proliferate in vitro. Conditioned medium from activated monocytes significantly (P less than 0.001) stimulated proliferation of SMC within 6 days of culture while media from non-activated monocytes was less effective (P less than 0.01). Non-vascular smooth muscle cells (human myometrium) were less responsive to such media (P less than 0.01 and P less than 0.05, respectively). These findings suggest that blood monocytes may play a key and until now unsuspected role in arterial smooth muscle proliferation, a recognized event in the initial stages of atherogenesis.
Blood Cells↗
Ultrasonic features of pneumatosis intestinalis.
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Adult↗
Juvenile atherosclerosis and Reye's syndrome.
Four patients, three girls and one boy, ages 8 to 14 years, with clinical and pathological findings of Reye's syndrome, were found to have an unusual degree of intimal thickening in the coronary arteries and advanced fatty streaks in the aorta. It is suggested that viral infection or metabolic abnormalities may have played a role in their development. A careful examination of the cardiovascular system in children with this and other diseases of probable infectious etiology is emphasized.
Adolescent↗