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Biomedical subjects

A L Weiman

Publications and source records attributed to A L Weiman.

7 recordsLinked to original sources
PubMed2001

Use and cost of outpatient visits of AD patients: CERAD XXII.

OBJECTIVE: To determine the probability, frequency, and cost of outpatient visits of patients with AD in the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) as a function of stage of dementia and institutional status. METHODS: Clinical information on 388 patients with AD enrolled in CERAD who had no serious comorbidities at baseline and for whom the stage of disease and institutional status were known, were linked to Health Care Financing Administration Physician/Supplier and Outpatient Standard Analytic (institutional outpatient) files for 1991 through 1995. None was registered in a health maintenance organization. Repeated measures regression models were used to examine the relationship of stage of disease to probability, frequency, and cost of outpatient visits for institutionalized and noninstitutionalized patients, with demographic characteristics and calendar time controlled. RESULTS: The annual proportion of patients with AD and a Medicare-reimbursed outpatient visit ranged from 81% to 95% and was not related to stage of dementia or institutional status. Among those with at least one outpatient visit, however, those living at home had fewer visits than did those in institutions, but their number of visits increased as dementia worsened. Those in institutions had a larger number of outpatient visits, but these did not vary significantly by stage of dementia. Neither location of residence nor stage affected the cost of outpatient visits. CONCLUSION: Among those with an outpatient visit, the frequency of visits and their relationship to stage of disease depends on institutional status.

Aged↗
PubMed2001

Use and cost of hospitalization of patients with AD by stage and living arrangement: CERAD XXI.

OBJECTIVE: To determine the probability, frequency, length of stay, and Medicare costs of hospitalization of institutionalized and noninstitutionalized patients with AD at various stages of dementia. METHODS: The authors analyzed the 1991 to 1995 Medicare records of 420 CERAD patients with AD, a group which, at entry, had no serious comorbidities. They were geographically distributed across the United States and observed for a median of 2.5 years. Repeated measures logistic regression and generalized estimating equations were used to model the probability of hospitalization. Among those hospitalized, the general linear mixed model was used to determine number of admissions, length of stay, and Medicare cost. Demographic characteristics and calendar date were controlled in all analyses. RESULTS: As dementia worsened, the probability of hospitalization increased among patients living at home, but decreased among those who were institutionalized. Number of admissions, length of stay, and cost also decreased significantly as stage worsened among the institutionalized patients, but the stage of dementia had no effect in non-institutionalized patients. CONCLUSION: The hospitalization experience of patients with AD living at home differs from that of patients with AD living in institutions. Residential setting appears to be an important determinant of hospitalization in patients with AD.

Aged↗
PubMed2000

Frequency and duration of hospitalization of patients with AD based on Medicare data: CERAD XX.

Medicare records on 477 Consortium to Establish a Registry for Alzheimer's Disease patients with AD for 1991 through 1995 showed a hospitalization rate of 0.37/person-year with a length of stay of 3.7 days/ person-year (average of 10 days/hospitalization). Unmarried and less-educated patients with AD were admitted to the hospital more frequently, and, along with black patients, had a longer length of stay. Frequency and duration of hospitalization were greater in the patients with AD than in Medicare beneficiaries in general, but the rate of diagnostic/therapeutic procedures was lower.

Alzheimer Disease↗
PubMed1984

Effects of predictors of hemispheric specialization on individual differences in hemispheric activation.

In two studies predictors of variation in hemispheric specialization--handedness, sex, familial history of sinistrality, writing posture and sighting dominance--were found not to be independent of individual differences in characteristic activation asymmetry. Predominant direction of conjugate lateral eye movements was used to assess activation asymmetry. The lack of independence between these two dimensions of individual difference, predictors of variation in hemispheric specialization and in activation asymmetry, suggests caution in interpreting the results of studies in which one dimension is examined and the other is uncontrolled.

Adult↗
PubMed1984

Asymmetry of the face at rest: size, area and emotional expression.

In a sample of 53 right-handed, young adult males, asymmetry was examined in the size of 11 facial regions, in total area, and in emotional expression of the face at rest. In the complete sample no evidence was obtained of consistent asymmetry in size of facial regions, in facial area, or in emotional expression. There was, however, an interaction between family history of sinistrality and sighting dominance in facial asymmetry for the pleasantness/unpleasantness of facial expression. The findings suggest that previously established asymmetries in phasic emotional displays are not an outcome of expressive or morphological asymmetries of the face at rest.

Adult↗
PubMed1982

Hemispheric asymmetry in the expression of positive and negative emotions. Neurologic evidence.

Three retrospective studies were conducted to examine functional brain asymmetry in the regulation of emotion. In the first study, reports of 119 cases were collected of pathological laughing and crying associated with destructive lesions. Pathological laughing was associated with predominantly right-sided damage, whereas pathological crying was associated with predominantly left-sided lesions. In the second study, 19 reports detailing mood following hemispherectomy were collected; right hemispherectomy was associated with euphoric mood change. In the third study, lateralization of epileptic foci was assessed in reports of 91 patients with ictal outbursts of laughing (gelastic epilepsy). Foci were most likely to be predominantly left-sided. The findings are congruent with studies of the effects of unilateral brain insult on mood, and a general model of hemispheric asymmetry in the regulation of emotion is presented.

Adolescent↗