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Biomedical subjects

A L Yettram

Publications and source records attributed to A L Yettram.

12 recordsLinked to original sources

Factors influencing left-ventricular stiffness.

The aim of the study was to investigate the relative contributions of geometrical and material factors to overall left-ventricular cavity stiffness. Left-ventricular cavity shapes were reconstructed using a computer and the variation of myocardial elastic modulus was calculated, by the finite element method, through the passive phase of diastole when rising volume coincided with rising pressure. Geometric data were obtained from biplane cineangiography, with micromanometer pressure measurements, for ten patients with left ventricular disease. Dimensional analysis was applied to the initial and derived data from which the influences of myocardial compliance, wall thickness-to-long dimension ratio, and aspect ratio (long-to-short axes) were determined. The ratio between the volume elasticity and the myocardial modulus of elasticity, the normalized stiffness ratio (NSR), is proposed as a useful index of left ventricular mechanical behaviour in diastole. The volume elasticity of the chamber is dependent not only upon the myocardium elastic modulus and the wall thickness ratio, but also on the shape of the chamber. Changes in the thickness/radius ratio of the ventricle have less effect upon its distention than those in the long dimension/radius ratio. The left ventricle becomes more spherical in shape through diastole and hence becomes stiffer by this geometric mechanism.

Cineangiography

Relation between intraventricular pressure and volume in diastole.

The pressure-volume curves for 10 patients with various types of heart disease were studied throughout mid to late diastole when both pressure and volume were increasing. The results were used to test a currently held theory that the form of this relation is exponential. It was found that for the patients examined this hypothesis was not valid.

Adult

Effect of interface conditions on the behaviour of a Freeman hip endoprosthesis.

The femoral element of a total hip replacement is a composite structure of two, or perhaps three, components--the endoprosthesis, the bone and, where present, the cement. The interfacial conditions are such that complete structural continuity does not necessarily obtain. That this is so has often been suspected due to the observed loosening which can occur in vivo. In modelling the system, typically for finite element analysis, it has usually been considered to be monolithic, such that tensile and shear stresses could be transmitted across the interfaces as well as the normal compressive stress. Here the femoral component of a Freeman hip replacement is considered, implanted without bone cement, and analyses are carried out under monolithic, i.e. fully bonded, and non-bonded assumptions. Simultaneously the effect of retaining the neck of the femur, one of the features of using this particular prosthesis, is also examined.

Biomechanical Phenomena

Reactive force distributions for teeth when loaded singly and when used as fixed partial denture abutments.

1. A finite element model was devised to examine mechanical responses of the periodontium to loads applied to the model in vertical, oblique, and horizontal directions for an individual tooth having varied alveolar levels, splinted teeth, and a cantilever type of fixed partial denture. 2. Forces applied to the teeth are balanced by stresses generated within the periodontal membrane and alveolar bone. 3. It was substantiated that the teeth were evolved to carry axial types of loads, since stresses on the periodontium were smaller than those obtained for oblique or horizontal types of loads. Axial types of loads produce compressive stresses on the periodontium; oblique or horizontal types of loads produce zones of compressive and tensile stresses. 4. Mechanically, splinting teeth is a desirable procedure. 5. A cantilever type of fixed partial denture should have at least two abutments. It should not be used to replace more than one tooth.

Alveolar Process

An analytical investigation into possible mechanical causes of bone remodelling.

Three-dimensional finite element analyses were carried out on idealisations of two situations where bone remodelling has been reported clinically viz. the malaligned femur and a maxillary central incisor under orthodontic loading. The mechanical responses, i.e. stress, strain and change of curvature, in various directions, are presented. They are compared with the biological response, either bone resorption or bone deposition. The results are discussed in relation to three current theories of bone remodelling.

Alveolar Process

Biomechanics of the femoral component of total hip prostheses with particular reference to the stress in the bone-cement.

Two-dimensional finite element analyses were used to determine the normal and shear stress distributions at the prostheses-cement and cement-bone interfaces in the femoral component of a total hip replacement. Various combinations of stem, cement and bone stiffnesses were investigated. In particular the influences of stem taper, cement stiffness, prosthesis stiffness and the effect of a plateau, on the cement stresses were examined and compared. It was particulary noticeable that the normal direct stress across the cement in the proximal region of the stem, both literally and medially, as generally compressive. It was found that the more flexible the cement the more uniform were the stress distributions. Furthermore, these stresses increase as the stiffness of the stem decreases.

Biomechanical Phenomena

Analysis of left ventricular behaviour in diastole by means of finite element method.

The human left ventricle in diastole can be modelled as a passive structure with incremental internal pressure change being considered as the load. Recent developments in engineering stress analysis provide techniques for predicting the behaviour of structures with complex geometry and material properties, as is the case with the left ventricle. That which is most appropriate is the finite element method which requires the use of a large digital computer. The ventricles of 2 patients have been studied during diastole, the geometries having been derived from cineangiographic data (biplane), and the pressure by means of catheter-tip manometers. Various descriptions of myocardial stress/strain relations have been assumed and applied to the left ventricular wall in order to obtain the best match between the calculated and observed deformation patterns. The manner in which the value and distribution of stiffness in the left ventricle influences the shape change can therefore be determined, and possible clinical implications deduced.

Diastole

Finite element stress analysis of the crowns of normal and restored teeth.

Stress distributions are presented for a normal and a restored mandibular second premolar under masticatory-type forces. These were obtained using the finite element method of stress analysis applied to two-dimensional models. The effect of the relative stiffness of the materials is examined in each instance.

Bicuspid

Finite element stress analysis of a class I amalgam restoration subjected to setting and thermal expansion.

Stress analyses are presented for a second mandibular premolar with a class 1 amalgam restoration. The effects of amalgam setting and thermal expansions are examined. An axisymmetric representation of the structure is used and the analyses are carried out by the finite element method. Lined and unlined restorations are compared with regard to the principal stresses set up in the composite structures and also the patterns of deformation incurred. The effects of various enamel and dentin stiffness combinations are also considered.

Chemical Phenomena