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Biomedical subjects

A Lüdtke-Handjery

Publications and source records attributed to A Lüdtke-Handjery.

At least 19 recordsLinked to original sources
PubMed1993

[Heparin-associated thrombocytopenia as a problem in heparin therapy].

The clinical picture of HAT (heparin-associated thrombocytopenia) is being described in reference to a typical case report. If not recognized in time, HAT may lead to serious thrombo-embolic complications, which may eventually lead to death. Considering the wide applications of routine heparin in therapy and prophylaxis, HAT deservers more clinical attention. Routine monitoring of platelet counts during heparin treatment is crucial and essential.

Aged↗
PubMed1991

[Goblet cell carcinoid of the vermiform appendix].

The goblet-cell-carcinoid of the appendix vermiformis lies somewhat between the carcinoid and the adenocarcinoma of the appendix concerning the biological behaviour and the histological characteristics. Referring an own well documented case (76 are well known in the available literature) the importance of the very conscientiously managed histological examination of each appendix specimen is emphasized with regard to the 5-year-survival of 73%.

Appendectomy↗
PubMed1991

[Has the dynamic hip screw justifiably replaced Ender nailing in the management of hip para-articular femoral fractures of the A1-A3 and B2 type?].

The results obtained in 167 extracapsular fractures of the hip are presented. Ender's pins were used in 82 cases and the dynamic hip screw (DHS) in 85. Comparison of different aspects (handling, postoperative mobility, complication rate, mortality) shows that the second operating procedure named DHS is highly suitable for the treatment of fractures A1-A3 and B2 (Müller classification) and superior to the procedure with Ender's pins.

Aged↗
PubMed1990

Long-term follow-up of posttransfusion and sporadic chronic hepatitis non-A, non-B and frequency of circulating antibodies to hepatitis C virus (HCV).

The natural course of chronic hepatitis non-A, non-B (HNANB) was documented for 3-20 yr (mean 8 yr) in 86 patients, who attended our special ambulance between 1981 and 1988. Sixty five of the 86 patients (75%) were positive for circulating antibodies against hepatitis C virus (HCV) (anti-HCV). Twenty four patients had chronic posttransfusion (PT)-HNANB (18 anti-HCV-positive; 75%), and 62 patients had sporadic (S)-HNANB (47 anti-HCV-positive; 75%). Twenty nine per cent of patients with chronic PT-HNANB had sustained normalization of aminotransferases after a period up to 5 yr, 55% demonstrated chronic persistent hepatitis (CPH) and 16% progressed to chronic active hepatitis (CAH) with transition to cirrhosis. In the group with chronic S-HNANB, 2% of patients showed remission, 43% had stable CPH and 55% progressed to CAH or cirrhosis. However, development of cirrhotic complications required many years. Transition from CAH to CPH or remission was not observed. The results indicate that 75% of both patients groups with chronic PT- and S-HNANB are infected with the same agent, of which antibodies are detected by the new anti-HCV assay. There was no statistical association between the severity of the disease and the presence of anti-HCV. The different proportions of progressive courses in chronic PT- and S-HNANB might be explained by the patient recruitment.

Blood Transfusion↗
PubMed1983

Are axillofemoral bypass grafts worthwhile? A 10-year review.

Axillofemoral grafts (144 prostheses: 103 unilateral, 25 bifemoral = y-shaped, and 8 bilateral) were performed in a total of 136 patients with aortoiliac occlusion. The average patient was 69 years old. Surgery was indicated only in "high-risk patients" in either stage II (n = 7; walking distance until onset of pain less than 50 m), stage III (n = 55), or stage IV (n = 74). Early occlusion of the prosthesis occurred in 26 cases; 15 were treated successfully by remedial surgery. The total rate of infection after first and remedial operations was 9.7%. The amputation rate, both early and late, was 19%. The early results showed that 114 patients had reached stage II (walking distance until onset of pain over 100 m). The postoperative follow-up period of up to 116 months (average 27.6 months) revealed that the implanted prosthesis had remained patent in 80% of each group of patients at different postoperative intervals. This is extraordinary considering their length and course. Four fifths of the patients lived an average of 22 months, remaining in stage II without loss of limb(s); we believe it made their life more worth living. We conclude that axillofemoral grafts yield satisfactory results for a selective group, namely the "high-risk patient" with aortoiliac occlusion.

Arterial Occlusive Diseases↗
PubMed1983

[Postoperative peritonitis].

About 50% of relaparotomies in the early postoperative period are caused by peritonitis, the lethality ranges from 32 to 88% (average 56%). The most frequent reasons for the development of peritonitis following abdominal surgery are presented as well as the possible way to early diagnosis of this complication. In view of the poor prognosis an aggressive proceeding in therapy is necessary: referring to the results published since Starlinger (1954) the importance of an early decision for relaparotomy in order to raise the survival rate is pointed out.

Female↗
PubMed1981

[Surgically correctable cerebrovascular insufficiency].

Obstructions along supra-aortic branches cause one third of all cases with clinically obvious cerebrovascular disease. 80% of these alterations (stenosis, occlusion) can successfully be operated on. This paper deals with some facts concerning normal and pathological physiology of cerebral blood-flow as well as with clinical signs and staging of cerebral insufficiency. It offers aspects of the modern way of diagnosis and surgical therapy in cerebrovascular disease, caused by extracranial localized arterial obstruction. In conclusion, the search for an occlusive process being obligatory for prevention of stroke in any case of syncope or transitory neurological deficit is emphasized.

Carotid Artery Diseases↗
PubMed1977

[Surgical treatment of ischaemic cerebro-vascular accidents (author's transl)].

23 patients were operated on between 3 and 24 hours (group 1) and between 2 and 14 days (group 2) after a stroke with a diagnosis of carotid obstruction. A retrospective study for patients of stage IIIa and IIIb showed that clinical and functional results of both groups correspond. The mortality of group 1 was slightly less than that of group 2. Group 1 showed the largest number of successful vascular reconstructions. Thus an early operation of stage IIIa and possibly IIIb seems indicated. In view of the high mortality (5 out of 6 patients) surgery cannot be recommended in stage IV.

Acute Disease↗