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Biomedical subjects

A Lamotte

Publications and source records attributed to A Lamotte.

11 recordsLinked to original sources

Comparative chemical analyses of drug samples: general approach and application to heroin.

The methodology used for the comparative chemical analyses of illicit drug seizures, and its application to a heroin comparison case, is described. The illicit drug sample is subjected to a three-step procedure. The first is the qualitative and quantitative analysis of each sample, i.e. identification and quantitation of major and minor constituents. The second is the analysis of trace level impurities contained in each sample, after isolation from the drug matrix. The last step is the isotopic analysis of each sample, i.e. the determination of the isotopic enrichment of the major constituents. That analytical procedure, applied to heroin, allowed the determination of common batch samples with a high degree of certainty.

Drug Contamination↗

[Investigation of the thrombo-embolic disease by simultaneous lung scintigraphy and lower limb gamma-phlebography (author's transl)].

A venous thrombosis in the territory of the inferior vena cava and a possible embolus of the lung can be detected in one single examination by injecting 99 m Tc microagregates into a dorsal blood flow by this method, which associates radionuclide phlebography of the lower limbs and lung scanning, was carried out 140 times in 127 patients and resulted in the detection of 107 cases obliged us to investigate only one limb, gamma-phlebography appears to be a harmless procedure well suited to the study of the thrombo-embolic disease.

Humans↗

[Recent myocardial infarction. Study of sinus function].

The ECGs of 70 consecutive patients hospitalised for a first transmural myocardial infarction (MI) (28 anterior, 42 posterior) were analysed prospectively and systematically during the acute phase. Endocavitary electrophysiological studies (EEP) were performed on the 21st day. The following conclusions were drawn: --Sinus bradycardia in the acute phase was observed in 18 cases (26 p. 100). Its cause is uncertain and its occurrence has no relation to the site of infarction. The single case of sinoatrial block (SAB) was recorded in a patient with a posterior MI. --EEP were normal in 18 patients who had sinus bradycardia during the acute phase; EEP was clearly pathological in the case with SAB. --There was no statistical difference in the incidence of pathological EEPs (p greater than 0,05) in anterior (4 out of 28 patients) and posterior (5 out of 42 patients) MI.

Adult↗

[Paroxysmal junctional tachycardia with simultaneous supra-nodal and infra-nodal 2/1 block].

It is rare to find 2:1 second degree block in paroxysmal junctional tachycardia. In the case described, atrial stimulation at 200/mn during supra-ventricular tachycardia triggered off simultaneous atrio-ventricular and ventriculo-atrial block. This unusual occurrence was very useful because it localised the re-entry circuit to the junctional region by excluding possible accessory pathways.

Aged↗