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Biomedical subjects

A Lassaletta Atienza

Publications and source records attributed to A Lassaletta Atienza.

6 recordsLinked to original sources

[Neuroblastoma presenting as obstructive jaundice].

Obstructive jaundice as a presentation of abdominal tumors in childhood is extremely rare. To date, only 4 cases of neuroblastoma causing obstructive jaundice at diagnosis have been reported in children. We report a 4-year-old boy who presented to the emergency department with abdominal pain, jaundice, choluria and acholia. A diagnosis of unresectable, nonmetastatic neuroblastoma was made. Chemotherapy reduced the size of the tumor and relieved the symptoms of obstructive jaundice without the need for decompressive surgery. Abdominal tumors should be included in the differential diagnoses of obstructive jaundice in childhood.

Abdominal Neoplasms↗

[Subacute sclerosing panencephalitis: a still existing disease].

Subacute sclerosing panencephalitis (SSPE) is a rare entity with an invariably fatal course that progressively affects the central nervous system. It is caused by persistent infection with the wild-type measles virus. While rare in industrial countries, it is not infrequent in developing countries, where there are still areas of endemic measles infection and immunization is not yet generalized. We describe an eight-year-old Spanish girl who presented rhythmic and symmetric myoclonus. She contracted measles at 13 months and required hospitalization. No cognitive deterioration was found. Neuroimaging and the initial electroencephalogram were normal. Oligoclonal bands and high titers of measles antibodies were found in serum and cerebrospinal fluid. She was treated with oral metisoprinol and intraventricular alpha-interferon (IFN-) and showed no further progression of her symptoms. The importance of including SSPE in the differential diagnosis of patients consulting for school failure, neurological deterioration or movement disorders is highlighted. Special attention should be paid to the immigrant population from countries where the incidence of SSPE is greater than in Spain.

Antibodies, Viral↗

[Variables influencing duration of hospitalization for urinary tract infection].

BACKGROUND: The need for hospitalization and its duration in children with urinary tract infections (UTI) are controversial. OBJECTIVE: To analyze the effect of certain clinical factors from the medical records of children hospitalized with UTI to determine which factors have the greatest influence on length of hospital stay. MATERIAL AND METHODS: A retrospective study of the medical records of 93 patients admitted to our department with a diagnosis of UTI between May 1998 and June 2000 was carried out. All cases were confirmed by bacteriological analysis. The variables analyzed included age, sex, duration of fever before and during admission, temperature, length of intravenous antibiotic therapy, administration of aminoglycosides, presence of urinary tract malformations, previous episodes of UTI, and length of hospital stay. RESULTS: The variables with the greatest influence on a length of hospital stay of more than 7 days were age, especially an age of less than 24 months (OR 3.42; 95 % CI 1.2-9) and the number of days with fever during hospitalization (more than 2 days: OR 2.73; 95 % CI 1.07-7.6). CONCLUSION: Patient age significantly influences length of hospital stay in children with UTI. To optimize resources, ambulatory treatment of children with UTI should be encouraged, even in those younger than 2 years.

Aminoglycosides↗