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Biomedical subjects

A Laudati

Publications and source records attributed to A Laudati.

15 recordsLinked to original sources

[Familial metaphyseal dysplasia: incidental detection of an osteochondroma].

The authors take advantage of an incidental observation of osteochondroma in a patient affected by familial metaphyseal dysplasia to look further into the study of this congenital osteopathy. Examination of the family medical background brings to light the blood-relation of the patient's parents and the presence of the same clinical and radiological features in the patient's sister. Particular attention is given to histological and ultrastructural study of the removed bone tissue.

Adult↗

[Osteoid osteoma: ultrastructural aspects].

The authors take into consideration the ultrastructural aspects of osteoid osteoma and discuss the cellular and subcellular features of this neoplasm. Special attention is given to functional adaptability, which is specific for this type of cell, related to the degree of development of the neoformation.

Calcaneus↗

Nerve fibres in osteoid osteoma.

Many authors have attempted to explain the mechanism of pain in osteoid osteoma and, in the past, several histological studies have been carried out with the specific aim of verifying the existence of nerve fibres within the tumour. The histochemical procedures based on the affinity of nerves for silver stains have made it possible to demonstrate the presence of fine nerve fibres disposed alongside and around the vessels. An analogous study was conducted to confirm this and to supply further morphological and functional information useful for an understanding of the genesis of pain. The study involved three cases of osteoid osteoma using both traditional histochemical procedures and electron microscopy. The latter, in particular, allowed us to confirm the myelinic nature of the nerve fibres observed under optic microscopy. Based on these observations, the authors present a hypothesis on the function of the nerve fibres in the mechanism of pain stimulation.

Bone Neoplasms↗