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A Lavin

Publications and source records attributed to A Lavin.

23 records · Page 2Linked to original sources
PubMed1986

Electrophysiological changes in substantia nigra after dynorphin administration.

The present experiments were designed to explore the electrophysiological changes induced by dynorphin (Dyn) which was administered by pressure ejection into the zona reticulata of the substantia nigra (SNR). Dyn produced a long-lasting (6.0 +/- 4.5 min) decrease in firing rate in 70% of the cells recorded. Naloxone reversed the Dyn-induced decrease in firing rate in all cases, and also induced an increase in firing frequency on most occasions. Dyn did not alter cell activity in 8 of the 10 cells recorded in zona compacta of substantia nigra. It is concluded that Dyn exerts an inhibitory effect on SNR neurons, which appears to be pharmacologically specific since it is reversed by naloxone.

Animals↗
PubMed1985

Enzymatic removal of bilirubin from blood: a potential treatment for neonatal jaundice.

Current treatments for severe jaundice can result in major complications. Neonatal jaundice is caused by excessive accumulation of bilirubin in the blood. A small blood filter containing immobilized bilirubin oxidase was developed to reduce serum bilirubin concentrations. When human or rat blood was passed through the enzyme filter, more than 90 percent of the bilirubin was degraded in a single pass. This procedure may have important applications in the clinical treatment of neonatal jaundice.

Animals↗