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Biomedical subjects

A Layton

Publications and source records attributed to A Layton.

At least 19 recordsLinked to original sources
PubMed2000

Observations on high levels of fusidic acid resistant Staphylococcus aureus in Harrogate, North Yorkshire, UK.

A retrospective study was carried out to investigate possible reasons for a marked increase in fusidic acid-resistant Staphylococcus aureus (FusR S. aureus) identified by our routine hospital microbiology service. Information was obtained on a sample of 64 consecutive patients from whom resistant S. aureus had been cultured. The source of isolates was found to be diffuse within the hospital and community. The site of sample was most frequently chronic cutaneous infections (68%). All the S. aureus isolates were resistant to both fusidic acid and penicillin and many were resistant to multiple antibiotics. Topical fusidic acid had been used by 40% of patients in the preceding 6 months and none had received oral fusidic acid (sodium fusidate). Most (80%) had received an oral antibiotic in the preceding 2 years. Information from the Prescriptions Pricing Authority revealed that the total number of prescriptions for fusidic acid-containing preparations for the period September 1997 to August 1998 was markedly higher in Harrogate than in five other local areas where increases in (FusR) S. aureus have not been observed.

Administration, Oral↗
PubMed1991

Level of knowledge and information sources used by patients with psoriasis.

One-hundred and eight patients with psoriasis completed a questionnaire concerning their knowledge about the condition. This was carried out at two departments of dermatology, at Bridgend General Hospital and Leeds General Infirmary. There were no significant differences between the two centres, and the main source of the patients' information about psoriasis was from a dermatologist, but several other sources such as newsletter were of help.

Adolescent↗
PubMed1982

Reduced acuity and its relation to blur threshold measurements in optometric tests.

Sensitivity to blue was investigated in a group of subjects having long-standing reduction of visual acuity, and in another group of subjects whose acuity was reduced for the purpose of the study. The distributions of scores was compared with those of a previous study of subjects with normal acuity. The reduction of acuity produced a shift in both distributions, the greater shift occurring in the second group.

Adolescent↗
PubMed1978

Perception of blur in optometric test.

Sensitivity to blur detection was measured for 30 optometric patients by having them match the clarity [or blur] of the target words at the test endpoint with 1 of an identical set of photographically defocused words. The group showed considerable variance in their blur scores which approached a normal distribution. Some clinical implications are discussed.

Adolescent↗
PubMed1975

A supplementary technique for balancing refraction.

The customary technique for balancing the refractive (subjective) correction lenses requires the subject to compare the clarity of two images. If there is an inequality in the best acuity attainable for each eye, this technique does not give valid results. An alternate technique is described that does not depend upon maximal acuity for each eye.

Humans↗
PubMed1975

Retinal and post-retinal components of visual illusions.

A technique is presented permitting control of input to each hemiretina and each hemisphere, of the various elements of a visual illusion. When the retinal effects and post-retinal effects are added, the result is greater than the total illusory effect. This is believed due to the mixing between hemispheres via the corpus callosum, and suggests a possible means of assessing the role of the corpus callosum.

Corpus Callosum↗
PubMedDate not supplied

Molecular site assessment and process monitoring in bioremediation and natural attenuation. off.

A variety of modern biotechnical approaches are available to assist in optimizing and controlling bioremediation processes. These approaches are broad-ranging, and may include genetic engineering to improve biodegradative performance, maintenance of the environment, and process monitoring and control. In addition to direct genetic engineering strategies, molecular diagnostic and monitoring technology using DNA gene probing methods and new quantitative mRNA analytical procedures allows direct analysis of degradative capacity, activity, and response under in situ conditions. Applications of these molecular approaches in process developments for trichloroethylene (TCE), polychlorinated biphenyls (PCB), and polynuclear aromatic hydrocarbons (PAH) bio-oxidation in soils, aquifer sediments, and ground-water treatment reactors have been demonstrated. Molecular genetic technologies permit not only the development of new processes for bioremediation, but also new process monitoring, control strategies, and molecular optimization paradigms that take full advantage of vast and diverse abilities of microorganisms to destroy problem chemicals.

Bacteria↗