PubMed Health⌕ Search

Biomedical subjects

A Lazo

Publications and source records attributed to A Lazo.

29 records · Page 2Linked to original sources
PubMed1987

Embolization in cataclysmal hemorrhage caused by squamous cell carcinomas of the head and neck.

Cataclysmal hemorrhage occurred in eight patients with known aggressive squamous cell tumors of the head and neck. Angiography showed neovascularity, narrowing, beading of affected arteries, and pseudoaneurysms. Postembolization residual stump formation was seen in a few patients. A total of 11 embolization procedures were performed in these eight patients. Embolization materials included polyvinyl alcohol, isobutyl-2-cyanoacrylate, and detachable balloons. Survival times ranged from 5 to 274 days, with no deaths as a direct result of hemorrhage. Only one severe complication following embolization was noted.

Adult↗
PubMed1986

Identification by transfer blot of antigens reactive in the enzyme-linked immunosorbent assay (ELISA) in rabbits immunized and a calf infected with Cryptosporidium sp.

Soluble and particulate fractions of Cryptosporidium sp. oocysts from cattle were obtained by homogenization and sonication. Electrophoresis of the soluble fraction in polyacrylamide gels with sodium dodecyl sulfate and silver staining revealed the presence of 41 bands. Enzyme-linked immunosorbent assay (ELISA) of sera from rabbits immunized with either fraction and from a calf 40 days after infection showed that the animals produced specific antibodies. Enzyme-linked immunoelectrotransfer blot tests revealed the presence of five antigens with the rabbit sera and nine with the calf serum. ELISA proved to be an appropriate test for diagnosis of cryptosporidiosis. Selection of reactive antigens may improve the quality of diagnosis and/or reveal the presence of protective materials in the parasite.

Animals↗
PubMed1986

The silent brain infarct in carotid surgery.

The destructive potential of carotid artery disease is underestimated by the clinical classification that surveys only that part of the brain with clear somatic representation. Asymptomatic patients are found to have brain infarctions on CT scan for which there is no history or symptom. To assume "benign" behavior of a carotid lesion, a patient must be both asymptomatic and "asignomatic." Likewise, when the morbidity of carotid operations is reported, silent infarcts must somehow be taken into account. We investigated this "silent" disease in a prospective study of 100 carotid operations done on 91 patients over a 9-month period in our service. All patients had arch and four-vessel selective arteriography. Detailed neurologic examinations and CT scans were done before and after surgery. Of the 91 patients, 78 (86%) had a history of neurologic problems. Preoperative CT scans showed infarction in 21 patients, but only 57% of the infarctions correlated with symptoms and/or history. Among patients with a history of transient ischemic attack (TIA), 19% had an infarction seen on CT scan; however, among those patients who had lateralizing TIAs, the incidence of unsuspected infarction was higher (26%). Arteriography showed a lesion in all carotid systems supplying a symptomatic or infarcted hemisphere. Following 100 operations, four patients had neurologic abnormalities--two had transient hemianopsia and two had hemiparesis. CT scan showed a new infarct in all four patients as well as in eight other patients without neurologic findings; two of these silent postoperative infarctions were found in the hemisphere opposite the side of the operated carotid artery.(ABSTRACT TRUNCATED AT 250 WORDS)

Carotid Artery Diseases↗
PubMed1985

Familial systemic lupus erythematosus. Presence of a cross-reactive idiotype in healthy family members.

Sera of 27 members of 3 human kindreds with familial systemic lupus erythematosus (SLE) were examined for expression of a cross-reactive idiotype present on anti-DNA antibodies of SLE patients. By radioimmunoassay, serum samples from 6 of 8 SLE patients and 15 of 19 family members had high-titered reactivity with the antiidiotype, 3I. Isoelectric focusing and Western blot analysis of 3I-reactive bands revealed two patterns of reactivity: either a pattern of bands present at pH 5-7, or bands present at pH 5-7 with additional bands present at pH 7-8.5. Cationic bands were found to correlate with the presence of anti-DNA antibodies, indicating that immunoglobulin charge may be a factor in determining specificity for DNA. Millipore filter analysis revealed anti-DNA antibodies in sera of 4 of 8 SLE patients and 2 of 19 family members without SLE. In 2 additional SLE patients and 2 additional family members, anti-DNA antibodies were revealed when sera were analyzed under conditions that dissociate immune complexes. This study indicates that expression of an idiotype associated with anti-DNA antibodies is significantly increased in relatives of SLE patients and usually occurs in the absence of anti-DNA activity.

Antibodies, Antinuclear↗
PubMed1982

Arteriovenous vertebral fistulae: cure by combination of operation and detachable intravascular balloon.

The direct surgical treatment of vertebral arteriovenous fistulae (AVF) presents serious difficulty and risk. Techniques for intravascular occlusion or embolization have made the treatment of AVF safer and effective. However, the occlusion of an AVF involving the segment where the vertebral vein becomes a single vessel may result in pulmonary emoblization by the occluding material. A combined procedure involving ligation of the vertebral vein and detachable balloon occlusion of the fistula was used in two instances without complications and with complete cure of the AVF.

Adult↗
PubMed1981

Craniofacial mucormycosis: computed tomographic and angiographic findings in two cases.

Two cases of craniofacial mucormycosis are presented, stressing computed tomographic (CT) and angiographic findings. In the first case, successful embolization of a sphenopalatine artery pseudoaneurysm is shown. The second case demonstrates CT findings of ethmoidal sinus and frontal lobe inflammatory change. Ophthalmic artery occlusion is show. Obstructive venous changes within the orbit and cavernous sinus are displayed by means of orbital venography.

Adult↗
PubMedDate not supplied

MR imaging of compressive myelomalacia.

The authors studied retrospectively 42 patients with the magnetic resonance (MR) diagnosis of myelomalacia. Depending on MR findings, the patients were grouped into early, intermediate, and late stages of myelomalacia. Early stage myelomalacia patients presented with high intensity signal changes on T2-weighted images involving the width of the affected cord. The intermediate stage patients were characterized by varying degrees of cystic necrosis of the central gray matter, better seen on T2-weighted images. Central cystic degeneration, syrinx formation, and atrophy were prominent features of the late stage of myelomalacia. Ten patients had follow-up MR examinations within 6 months of initial imaging. Two of the four early stage myelomalacia patients showed improvement in the repeat studies. The follow-up scans of the six intermediate and late stage myelomalacia patients showed either no change or progression of disease. Early stage myelomalacia may be reversible, depending on the severity of the initial spinal cord injury. Magnetic resonance can serve as a useful tool in the assessment and management of myelomalacia patients.

Adolescent↗
PubMedDate not supplied

MR imaging of lytic changes in Paget disease of the calvarium.

The authors present two patients with Paget disease, both showing lytic changes in the calvarium. On T1 contrast sequences, the first patient demonstrated an extraaxial soft tissue mass in the temporooccipital region. This abnormality was hypointense to the adjacent normal diploic tissue. The second patient demonstrated a hypointense frontal abnormality on the T1-weighted sequence. Intracranial extension of this lesion was associated with lysis in otherwise mixed signal pagetoid bone. The first patient had osteoclastic Paget disease or osteoporosis circumscripta. The second patient had sarcomatous degeneration.

Aged↗