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Biomedical subjects

A Lefrançois

Publications and source records attributed to A Lefrançois.

At least 19 recordsLinked to original sources
PubMed2000

Oral and maxillofacial manifestations of multiple sclerosis.

Multiple sclerosis is a chronic demyelinating disease of the central nervous system which mostly affects young adults living in the northern hemisphere. It is a disease primarily found in temperate climates, being rare in the tropics and increasing in frequency with distance from the equator. Canada has one of the highest prevalence rates in the world. Dentists should be familiar with the clinical manifestations that affect the oral and maxillofacial areas as well as patients' general health. Three of the most frequent oro-facial symptoms include trigeminal neuralgia, trigeminal sensory neuropathy and facial palsy. Dentists should also be aware of the importance of this disease in the diagnosis, treatment and prognosis of certain oro-facial lesions or conditions. This paper reviews 2 cases of multiple sclerosis, highlights its oro-facial manifestations and discusses the dental implications of the disease.

Adrenocorticotropic Hormone↗
PubMed1998

[Rapid Tendency Oriented Perimeter (TOP) with the Octopus visual field analyzer].

PURPOSE: To study the capabilities of a new perimetric strategy with the Octopus visual field analyzer: the Tendency Oriented Perimetry. METHODS: Tendency oriented perimetry (TOP) attempts to assess the visual field by using answers to questions to establish thresholds in the neighboring area. We evaluated 79 visual fields with the Octopus strategy using the program 32 and the TOP strategy split into the following groups: normal visual field or glaucoma suspects (52), moderately advanced glaucoma (16), advanced glaucoma (11). The following parameters were analyzed for the two strategies studied: examination time, MS (means sensitivity), MD (mean defect), LV (Loss Variance), short term fluctuation (RF) and the number of points with a deficit with different p values: p < 0.5; p < 1; p < 2; p < 5. RESULTS: TOP perimetry showed a significant reduction of exploration time: 11.87 minutes with the Octopus 32 vs 2.49 minutes with the TOP strategy (p < 0.001). There is no significant modification for the other parameters (MD, MS, RF) except for the LV (Loss Variance) for the global analysis and for each separate group. CONCLUSION: The TOP strategy reduces examination time significantly but seems to be less accurate especially for the calculation of the depth of each scotoma in comparison with the standard Octopus 32 perimetry.

Adult↗
PubMed1989

[A case of MEWDS. "The multiple evanescent white-dot syndrome"].

A young white man developed acute bilateral visual loss with no previous general illness. Ophthalmoscopic examination showed multiple small yellow-white lesions scattered throughout the posterior poles and mild periphery fundus. There was also fine granularity of two foveal areas and one optic disc margin was blurred. Fluorescein angiography showed early hyperfluorescence of the lesions and late staining of the retinal pigment epithelium. Electrophysiologic abnormalities were transient, asymmetric, more marked in photopic than in scotopic. The origin could be in retinal bipolar cells. These lesions regressed, with return of normal visual function within several weeks. These clinical findings are different from others acute inflammatory diseases primarily involving retinal pigment epithelium and photoreceptors. This aspect is usually described as "multiple evanescent white dot syndrome". The etiology of this syndrome remains unknown with no evidence of systemic disease. A history of flulike illness is rare.

Adult↗
PubMed1981

[Acute retinopathy of prematurity following oxygen therapy: current concepts (author's transl)].

Five cases of retinopathy of prematurity have been observed among 1,750 premature infants at the Florence Geller Center in Cochin-Port-Royal--C.H.U. over a period of four years. In all cases, arterial PaO2 was more than 100 mmHg at least once. In the two worst cases, oxygen therapy given only during the first had been hours of life. The authors insist on the dangers of oxygen overdose immediately after birth or during transport to a Premature Infants Center. Laser photocoagulation was employed in four eyes: 2 with regression, 1 with cicatrisation, 1 with fibroplasia. Retinopathy of prematurity remains a danger in France, even if it is not as frequent as in the U.S.A. or Japan. Indirect ophthalmoscopy is essential for diagnosis and fluorography very useful to determine prognosis and treatment.

Acute Disease↗
PubMed1979

[Juvenile hemorrhagic ocular choroidopathy (author's transl)].

We observed in 13 young patients a serous or hemorrhagic paramacular detachment of one third to one half disc diameter size. In eight, we have seen also atrophic choroidal scars. In one patient the serous detachment occured at the site of a previously studied choroidal scar. Our cases resemble the presumed ocular histoplasmin choroiditis described in American literature. In our cases histoplasmosis can be excluded. Visual prognosis is dependent upon proximity of the choroidal lesion to the fovea. In most cases this prognosis is poor. The term juvenile hemorrhagic ocular choroidopathy is suggested for the disease.

Adult↗