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Biomedical subjects

A Leischner

Publications and source records attributed to A Leischner.

At least 19 recordsLinked to original sources

[Classical German brain pathology especially aphasiology--The Berlin Charity hospital].

The history of the classical period of German clinical brain pathology, especially aphasiology, is described. The present article covers authors, neuropsychiatrists and one phoniatrist, all of whom worked in Berlin before the First World War. The study aims at providing an insight into that most fruitful period to those who are presently concerned with assessment and treatment of aphasia and other neuropsychological disorders.

Aphasia↗

[Serial reactions in aphasic patients].

A symptom is reported that has hitherto not been described in neuropsychological literature: Not infrequently, severe aphasics mix automatized verbal series or parts of them not only into their spontaneous speech but also into other modalities of the expressive language. Sometimes this form of automatism replaces a demanded answer. In the speech data of 134 aphasics this symptom was observed in half of the cases. Its incidence was analysed in relation to aetiology, type of aphasia and the modalities in which it was observed. 6 cases are described in detail. The serial reaction is a neuropsychological sign of clinical value, because it indicates an organic brain lesion.

Aged↗

[Number agraphia].

One hundred and seventy-five aphasic patients (50 total, 50 mixed, 50 motor-amnesic and 25 sensory-amnesic aphasics) were tested for the writing to dictation of numbers with more than one digit. Twelve types of error were found. The percentages for the different types of error were determined for all subtypes of aphasic patients and for the total group of patients. In 98% of the aphasic subjects at least one or several types of error were ascertained. In all, 80.6% of the patients were unable to write correctly a number of three digits. Certain types of disturbances, such as macrographia, serial writing, perseveration and mirror writing, occurred more often when numbers were dictated than when words or letters were dictated. In the patients with sensory-amnesic aphasia these disturbances were found more often than in those with motor-amnesic aphasia. With respect to German-speaking patients, a particular type of error concerns the serial ordering of numbers with more than one digit (Stellenwertfehler). This type of error was found in 34.9% of our patients. Our results suggest standard examinations of aphasic patients should include the writing to dictation of numbers with more than one digit.

Agraphia↗

[The graphic disconnection syndrome].

A method is proposed for studying writing ability in both hands of agraphic aphasics with hemiplegia. In cases with agraphia performance when writing dictation was superior with the paralysed arm. Literal paragraphia was more frequent in the left hand and verbal paragraphia and perseveration were found exclusively on the left side. In a control group of aphasics with agraphia but without hemiplegia, these differences were not noted. It is concluded that this hitherto unknown phenomenon is caused by intersection of the path between the graphic region of the dominant hemisphere and the corpus callosum. Therefore the syndrome is termed "graphic disconnection syndrome".

Adult↗

Side differences in writing to dictation of aphasics with agraphia: a Graphic Disconnection Syndrome.

The performance of five aphasics with agraphia and right hemiplegia showing side differences in writing to dictation is reported on. It was found that writing with the paralyzed arm, supported by a writing aid, was better than writing with the left hand. In a control group of aphasics with agraphia, but without hemiplegia, such side differences were not found. The conclusion is drawn that in aphasia with hemiplegia the lesions intersect the path between the graphic region of the dominant hemisphere and the corpus callosum. Therefore the observed syndrome is termed "Graphic Disconnection Syndrome."

Adult↗

[Course studies of spontaneous speech and graphic achievements in 175 aphasics].

In 175 aphasic patients with agraphia the course of the expressive oral and graphic performances was compared. Spontaneous speech and writing and the writing of dictated words and sentences were investigated and evaluated. In addition, several peculiarities of this syndrome were examined. The investigations showed that the relationship between the expressive oral and graphic performances changes in the course of improvement depending on the type of aphasia. In the first period of testing no difference was found in the performances of patients with total aphasia and motor-amnesic aphasia; in the group of mixed aphasics and sensory-amnesic aphasics, however, the oral performance predominated the writing. Investigations at later periods showed that in the cases of total aphasia the improvement of the oral performance was better whereas in the cases of motor-amnesic and sensory-amnesic aphasia the graphic performance was more improved.

Agraphia↗

[Comparison between the oral and the graphic performance in 175 aphasics (author's transl)].

In 175 aphasics (50 global, 50 mixed, 50 motor-amnestic and 25 sensory-amnestic) the spontaneous oral and graphic performances were compared. They were quantified by means of a six-graded scale. In the group of global aphasics the same number of patients showed either identical or different results in both performances. Among the global aphasics which obtained different results, the number of patients with a better oral performance was identical with that of those who had a better graphic performance. In the other types of aphasia the results in both performances were mostly different. Mixed and sensory-amnestic aphasics were mostly better in spontaneous speech than in spontaneous writing. The motor-amnestic aphasics did not show such predominance in one performance. Therefore, during the improvement of aphasias the performances in spontaneous speech and in spontaneous writing can improve independently but to the stage of improvement seems to be a related factor.

Aphasia↗