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Biomedical subjects

A Lewandowski

Publications and source records attributed to A Lewandowski.

At least 37 records · Page 2Linked to original sources

Mezlocillin and carbenicillin: a clinical comparison of serious systemic infections in surgical patients.

Eighty patients suffering from severe cases of systemic surgical infections were enrolled in a prospective, controlled randomized study to compare mezlocillin and carbenicillin. The daily dosage was chosen according to international recommendation, i.e. 4 g mezlocillin 6-hourly and 5 g carbenicillin 4-hourly. A clinical, bacteriological and combined "overall" evaluation was made. There was a distinct trend in favour of the mezlocillin group which was not statistically significant. The treatment was well tolerated; no side-effects were observed.

Adult↗

Mezlocillin in serious surgical infections caused by carbenicillin-resistant bacteria.

Fifty-eight surgical patients suffering from severe bacterial infections caused by mezlocillin-sensitive, carbenicillin and/or gentamicin-resistant bacteria were treated with mezlocillin in 1980. At the end of therapy, the infection had been eliminated in 52 patients; they were cured. The remaining six did not need any additional antibacterial treatment. Sixty-two of the bacterial strains isolated had been eliminated, seven markedly reduced in number and three persisted. No development of resistance or side-effects was observed. A randomized comparative study was conducted at the same time.

Adult↗