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Biomedical subjects

A Leys

Publications and source records attributed to A Leys.

At least 19 recordsLinked to original sources
PubMed1991

Bilateral blindness in cavernous sinus thrombosis.

An unusual case of bilateral blindness secondary to a cavernous sinus thrombosis is reported. A woman who had undergone reconstructive surgery after tumor resection of the floor of the mouth, was readmitted 1 month later with bilateral proptosis and signs of sepsis. There were no complaints of blurred vision. A CT-scan of the orbits demonstrated a bilateral cavernous sinus thrombosis (CST) secondary to an infection at the skull base behind the myocutaneous flap. A few days later she became blind, due to bilateral central retinal artery occlusion and anterior ischemic optic neuropathy. The general critical condition improved with intensive AB treatment. The patient recovered well without neurological defects apart from her permanent bilateral blindness. There were no signs of tumor recurrence. To our knowledge, this is the first documented case of bilateral blindness in a patient suffering from CST.

Blindness↗
PubMed1991

Fundus changes in membranoproliferative glomerulonephritis type II. A fluorescein angiographic study of 23 patients.

A total of 23 patients aged between 11 and 64 years who had biopsy-proven membranoproliferative glomerulonephritis type II (dense deposit disease) were studied using fluorescein angiography of the retina. With the exception of two adolescents, all patients exhibited small subretinal nodules that were similar to basal laminar drusen. Subjects with a long history of renal disease displayed more numerous and larger nodules as well as atrophic changes. Four subjects presented with subretinal neovascular membranes.

Adolescent↗
PubMed1991

Specific eye fundus lesions in type II membranoproliferative glomerulonephritis.

In three adolescents, suffering from membrano-proliferative glomerulonephritis type II, ophthalmoscopy and fluorescein angiography revealed retinal pigment epithelium lesions, referred to as basal laminar drusen. The patient with the longest renal history had the most pronounced fundus changes. These lesions, earlier described in adult patients, are believed to be specific for this particular form of chronic glomerulonephritis.

Adolescent↗
PubMed1991

[Syndromes of the vitreo-macular interface].

Macular pucker, the vitreomacular traction syndrome and the macular hole are three conditions related to the vitreomacular interface. The role of the vitreous is different for each of these syndromes. Vitreous surgery aims at improving vision in the first two conditions. The role of preventive vitrectomy in the impending macular hole syndrome is still a matter of debate. The authors report their own experience and give a review of the recent literature on the subject.

Eye Diseases↗
PubMed1991

[Colobomatous pits and serous macular detachment].

Several congenital anomalies of the optic disc are associated with serous detachment of the macula or retinal detachment. Treatment of this condition, and hallmarks of disc and systemic anomalies are discussed.

Coloboma↗
PubMed1990

Subretinal neovascular membranes associated with chronic membranoproliferative glomerulonephritis type II.

Subretinal neovascular membranes were observed in three patients with chronic membranoproliferative glomerulonephritis type II (dense deposit disease). The first signs of glomerulonephritis occurred at respective ages of 13, 10 and 10 years; subretinal neovascular membranes were noted at respective ages of 25, 32 and 32 years. All patients had bilateral, widespread retinal pigment epithelial abnormalities. Our findings indicate that subretinal neovascularization is a complication of dense deposit disease. In one patient, the early recognition and laser treatment of an extrafoveal subretinal neovascular membrane prevented further loss of vision.

Adolescent↗
PubMed1990

Multiple evanescent white dot syndrome (MEWDS).

We describe the course of MEWDS (multiple evanescent white dot syndrome) in 2 young females. The first patient presented with a very pronounced macular edema. The second patient had merely optic disc edema. Both had an enlargement of the blind spot, which normalized later. Only the granular aspect of the fovea persisted in the involved eye.

Adult↗
PubMed1990

[Detachment with giant tear].

The authors report their experience in treating 39 eyes in 36 patients suffering a retinal detachment with giant tear. Follow-up has been from 7 to 54 months with a mean of 25 months. The different surgical procedures are compared and evaluated.

Adolescent↗
PubMed1989

[Behçet's disease: a study of 20 cases].

We observed 20 patients with ocular Behçet's disease. During the episodes of exacerbation the main features were: deep retinal infiltrates and vascular occlusions which were responsible for a sudden decrease in visual acuity. Also, there is posterior uveitis and retinal edema which persists during the whole course of the disease. In the final stages we observed an avascular, atrophic retina. Most patients also presented with a striking maculopathy and very often an atrophic optic disc was associated. On time of diagnosis, most patients were in their third decade, ranging from 19 to 61 years of age. Treatment consisted in administration of topical and systemic steroids. Most patients also required immunosuppressives and immunomodulators (cyclosporine A) in a later stage of the disease.

Adult↗
PubMed1989

[The clinical aspects of Vogt-Koyanagi-Harada disease in Belgium].

From a group of 13 patients, 4 developed a severe, relapsing anterior and posterior uveïtis with pronounced neurological and dermatological symptoms. The other 9 patients presented with similar, however more moderate symptoms. The majority of the patients regained a good visual acuity after the attacks of uveïtis. However the paracentral or central scotomas often continue to interfere with the reading ability.

Adrenal Cortex Hormones↗
PubMed1989

Management of macular pucker.

The history of 67 patients presenting with symptoms of macular pucker has been analysed retrospectively. Thirty-seven patients had a conservative follow-up. In 30 patients a pars plana vitrectomy with peeling of the premacular membrane has been performed. The natural course of the disease has been studied in the first group. For the second group surgical indications and results are discussed.

Adult↗
PubMed1989

[Choroidal melanoma and suspected naevi in diabetics].

Eight choroidal melanomata and 3 suspected naevi were observed in 11 diabetics. One xenon-arc treated tumor was followed up for 7 years; two tumors had Strontium90 radioactive plaque brachytherapy and their follow up was 3 years and 6 years.

Aged↗