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Biomedical subjects

A Loewy

Publications and source records attributed to A Loewy.

5 recordsLinked to original sources
PubMed1979

Regulation of teichoic acid synthesis during phosphate limitation.

Bacillus subtilis W-23, when placed in phosphate-free medium, ceases to synthesize teichoic acid and synthesizes teichuronic acid. The enzymatic basis for the cessation of teichoic acid synthesis is the irreversible inhibition of the first membrane-bound enzyme involved in teichoic acid synthesis which catalyzes the reaction Undecapenol-P + UDP-GlcNAc leads to undecaprenol-P-P-GlcNAc + UMP.

Bacillus subtilis↗
PubMed1979

Facial nerve repair with tissue adhesive.

The facial nerve in dogs was exposed, transected, and repaired by either of two methods. Suture and a Silastic sheath was the control method, since a review of the literature suggests it gives the highest rate of success. A tissue adhesive (Histoacryl) was used as the experimental method. In both techniques, the surgical microscope was used. Thirteen nerves were repaired: seven with the adhesive and six with suture and Silastic sheath. Success was judged on two criteria: (1) observation of motion in the muscles that were innervated after electrical stimulation of the nerve proximal to the repair site and (2) evaluation of microanatomical continuity after removal of the repair site and preparation of slides and tissues staining. The two repair methods produced statistically equal results. The "adhesive" method can be performed with greater ease and is less time-consuming. The number of studies required for statistical reliability was determined by means of sequential analysis.

Animals↗
PubMed1979

Control of teichoic acid synthesis during phosphate limitation.

The synthesis of teichoic acids was examined in Bacillus subtilis Marburg grown under conditions of phosphate limitation. The results indicate that the inhibition of polyglycerolphosphate synthesis observed under these conditions is the result of two processes. The first process is reversible and is independent of new protein synthesis; the second process is irreversible and requires the synthesis of new protein. During growth, under conditions of phosphate limitation, there is a slow decrease in the level of CDP glycerol pyrophosphorylase activity which is by itself not sufficient to account for the decrease in the rate of polyglycerolphosphate synthesis.

Bacillus subtilis↗