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Biomedical subjects

A Loh

Publications and source records attributed to A Loh.

17 recordsLinked to original sources
PubMed1992

Improved technique for polytetrafluoroethylene bypass grafting: long-term results using anastomotic vein patches.

Results of peripheral arterial bypass using polytetrafluoroethylene grafts have remained poor in comparison with those using saphenous vein grafts, particularly for anastomoses to tibial and peroneal vessels. A simple modification to the conventional operative technique, involving the incorporation of a vein patch into the distal anastomosis, has enabled considerable improvement. Five-year patency rates of 71 per cent for popliteal and 54 per cent for infrapopliteal grafts have been achieved in a series of 256 patients operated on between 1982 and 1989.

Aged↗
PubMed1992

Comparative tissue distribution of 125I- and U-14C-labeled recombinant human interleukin-2 in the rat.

The distribution of recombinant human interleukin-2 (rhIL-2) after intravenous administration of 125I- or U-14C-labeled rhIL-2 is reported in the major organs of the rat. Five minutes after the administration of U-14C-labeled rhIL-2, the radioactivity had been rapidly cleared from the plasma, while 38% of the dose was found in the kidneys, confirming that the major site of clearance for rhIL-2 is the kidney. After 1 h, a large fraction of the radioactivity had disappeared from the kidney and was found in the carcass. When the same experiments were carried out with 125I-labeled rhIL-2, comparable distribution results were obtained: Preferential accumulation of 125I radioactivity (37.4%) was found in the kidney at 5 min after iv administration of 125I-labeled rhIL-2. One hour after dosing 125I label was predominantly present in the carcass (46%) and skin (15%). Similar percentages of the dose of 125I or 14C radioactivity were present in other organs or tissues. The present study indicates a similar distribution of the radiolabel in selected tissue and organs regardless of whether 14C or 125I was employed.

Animals↗
PubMed1992

Anatomical repair of large incisional hernias.

We present a method of repair for large incisional hernias using lateral relieving incisions of the anterior rectus sheath. This is a modification of the methods previously described by Young (1), Hunter (2) and Maguire and Young (3). There were no recurrences in the 13 patients reviewed. Other methods of repair for large incisional hernias are discussed.

Hernia, Ventral↗
PubMed1991

Evisceration and other complications of abdominal drains.

Drainage following major abdominal surgery remains controversial. A case of small bowel evisceration through a Wallis drain site after an abdomino-perineal excision of rectum is reported as a complication of abdominal drainage.

Adenocarcinoma↗
PubMed1991

Roux-en-Y loop jejunal necrosis: another pancreatitis associated enteropathy.

Severe acute pancreatitis is frequently associated with systemic and local complications. Local sequelae include disorders of the stomach, duodenum, small and large bowel, collectively termed pancreatic enteropathies. We describe a patient with post-gastrectomy acute haemorrhagic pancreatitis which was complicated by necrosis and perforation of an intra-thoracic Roux-en-Y jejunal loop. This does not appear to have been previously reported.

Acute Disease↗
PubMed1978

Determination of ethinyl estradiol in human urine by radiochemical GLC.

A radiochemical GLC analysis was developed for 3H-labeled ethinyl estradiol in human urine. The technique was applied to the unconjugated and aglycone fractions of urine collected from women who were dosed orally with: (a) single capsules containing 2.0 mg of 3H-quinestrol (900 muCi) and 2.5 mg of unlabeled quingestanol acetate dissolved in sesame oil and (b) single tablets containing 100 microgram of 3H-quinestrol (86 muCi). Unconjugated ethinyl estradiol in Day 1 urine collections represented means of 0.02% of the high quinestrol dose and 0.12% of the low dose. Ethinyl estradiol glucuronide in the same collections represented means of 0.55% of the high drug dose and 1.35% of the low dose. The method could detect 1-ng quantities of 3H-ethinyl estradiol and 3H-quinestrol.

Adult↗
PubMed1977

Radiochemical GLC assay for nortriptyline in human plasma.

A novel method was developed for the assay of nortriptyline in plasma. After nortriptyline was extracted, it was acetylated with 3H-acetic anhydride; the quantity of 3H-acetylnortriptyline in the extract was determined by radiochemical GLC. The method is capable of assaying 5 ng of nortriptyline/ml of plasma. The instrumentation was assembled from commercially available components.

Acetylation↗
PubMed1976

Surface predominance of trace elements in airborne particles.

A number of minor and trace elements including Be, C, Ca, Cr, K, Li, Mn, Na, P, Pb, S, Tl, V, and Zn present in coal fly ash are found to be preferentially concentrated on the particle surfaces. Environmentally effective concentrations of these elements are thus much higher than indicated by conventional bulk analyses.

Air Pollutants↗
PubMedDate not supplied

Liquid chromatographic determination of narasin in feed premixes.

A liquid chromatographic (LC) method has been developed to determine narasin in feed premixes. Narasin is extracted from the premix with a methanol-water solvent, and the extracted solution is assayed by using LC. Recovery of narasin from a 12.5 g/lb premix is quantitative (100%), with a relative standard deviation of 1.44%. The results correlated well (coefficient 0.92) with a turbimetric bioassay method.

Animal Feed↗