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A Lonkar

Publications and source records attributed to A Lonkar.

4 recordsLinked to original sources

Allergenic nature of Parthenium hysterophorus.

Parthenin has been reported as the active allergen in Parthenium hysterophorus contact sensitivity. A study was carried out to test various chemical fractions of the plant for isolating and identifying the exact allergens. Two additional sesquiterpene lactones apart from parthenin have been shown to be allergenically active. Structures of these sesquiterpenoids are presented. Photopatch tests do not indicate a photosensitizing capacity for these compounds.

Allergens↗

An antigen from Parthenium hysterophorus Linn.

The increasing incidence of contact dermatitis due to the wild growth of the weed Partheium hysterophorus Linn. in many parts of India has prompted chemical analysis coupled with clinical testing to isolate the offending agent. Results are present to show that parthenin, a sesquiterpene lactone, is the major antigen which produces contact dermatitis in sensitive human beings.

Allergens↗