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Biomedical subjects

A Lozes

Publications and source records attributed to A Lozes.

6 recordsLinked to original sources

[Computerized records in vascular pathology. I. Basic elements].

Computerized processing of medical case-report data in angiologic practice should be conceived in two parts: the basic elements which define patients during their identification, and the specific disease-related elements. The basic file raises the problem of coding of data and of who does what. The choice of objectives and of coding is the responsibility of the doctor in charge of the project. Data processed should not be in his language only and cannot substitute for him when a decision has to be made. Collection and storage of data also fall within the medical field, apart from certain sections: identification of patients, intensive care, vascular explorations, the person directly concerned being either the secretary, the nurse or the doctor.

Computers

[Introduction to Doppler laser flow measurement. Study of cutaneous vascularization].

The microcirculatory unit, which links arterioles with venules, is responsible for metabolic exchanges with the interstitial tissues and for the regulation of skin temperature. The sympathetic system controls cutaneous vascularization. A satisfactory method for dynamic clinical investigation of skin vascularization, previously not available, is now possible with the Doppler laser flowmeter which provides relative measurement of blood flow in the microcirculation. Three studies were conducted using this simple technique. Changes in skin blood flow were recorded in healthy volunteers during physiological stress: reactive hyperemia, hot and cold reaction test, respiratory changes, postural modifications. In patients with arteritis, the immediate effects of lumbar sympathectomy on skin blood flow were measured. During exploration of patients with vasomotor disorders, the cold test was performed by exposing the extremities in a thermal chamber: laser flowmeter recordings provided data on specific alterations occurring during a disease or Raynaud's syndrome. These findings will assist quantification of, and the application of predictive tests to the most useful measures to adopt for vasomotor disorders.

Doppler Effect

[A thermal chamber for the cold test in vasomotor disorders].

The cold test represents an essential part of the functional exploration of the vascular system performed in Raynaud's disease, but its physiological nature depends upon the use of a sufficiently large area of skin. Several measurements must be conducted simultaneously and various temperature ranges used to allow for the variable threshold of vascular reactivity to cold of different individuals. A thermal chamber is presented which enables the simultaneous performance of plethysmography, digital pressure recordings and capillaroscopy at different temperature ranges. A novel use of a laser flowmeter is also described. Peri-ungual capillaroscopy enables determination of the temperature, when capillary spasm appears and then is relieved during progressive cooling followed by reheating. This apparatus can be adapted for use of all techniques for exploration of vascular function.

Cold Temperature

Venous plethysmography applied in pathologic conditions.

The correlation between venography and SGP in 41 patients was studied. Fourteen normal subjects were used as a reference. SGP was shown to be very sensitive (97.5%), including proximal and distal DVT, and highly specific (96.4%). After some recommendations for patient positioning and technical use, it will enhance both the accuracy and the reproducibility of plethysmography for evaluation of patients with suspected deep venous thrombosis.

Acute Disease

[The value of spectral frequency analysis by Doppler examination (author's transl)].

Arterial stenoses of moderate extent may involve modifications of the blood flow. Arterial shading is not always examined at the best incident angle to assess the extent of the stenosis. Spectral frequency analysis by Doppler examination is a good means of evaluating the effect of moderate arterial lesions. The present study was carried out with a Doppler effect having an acoustic spectrum, which is shown in a histogram having 16 frequency bands. The values were recorded on the two femoral arteries. A study was also made of 49 normal subjects so as to establish a normal envelope histogram, taking into account the following parameters: maximum peak (800 Hz), low cut-off frequency (420 Hz), high cut-off frequency (2,600 Hz); the first peak was found to be present in 81 % of the subjects (at 375 Hz) and the second peak in 75 % of the subjects (2,020 Hz). Thirteen patients with iliac lesions of different extent were included in the study; details of these lesions were established in all cases by aortography. None of the recorded frequency histograms were located within the normal envelope. Two cases of moderate iliac stenoses were noted ( Less Than 50 % of the diameter) which interfered with the histogram, even though the femoral velocity signal was normal.

Adult