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Biomedical subjects

A Lunderquist

Publications and source records attributed to A Lunderquist.

At least 55 records · Page 3Linked to original sources
PubMed1983

The peribiliary vascular plexus: the microvascular architecture of the bile duct in the rabbit and in clinical cases.

The livers of 30 rabbits were perfused with a silicone rubber solution (Microfil), underwent a clearing process, and were examined with a dissection microscope. The study showed distinct vascular plexuses in and around the bile duct, and two concentric vascular layers present within its wall: the inner capillary and the outer venous. Around the bile duct there was a fine arterial network and a larger venous plexus, which communicated with the capillary and venous plexuses of the bile duct, respectively. The venous plexuses drained directly into the sinusoids or indirectly through the portal vein. The microvascular architecture of the rabbit bile duct correlated well with clinical angiograms exhibiting normal and abnormal peribiliary vascular plexuses. The arterial and venous plexuses dilated and provided collateral circulation in both extrahepatic and intrahepatic arterial and portal vein occlusions, respectively. The peribiliary arteries may be dilated or encased in patients with cholangiocarcinoma or hepatocellular carcinoma invading the bile duct. The animal study and observations on angiograms suggest the existence of transplexal arterioportal communication.

Angiography↗
PubMed1983

Percutaneous transhepatic cholangiography and drainage. Risks and complications.

An analysis of 237 consecutive PTC/PTD procedures revealed radiographically demonstrable complications in 21 per cent (50/237 cases: bile-contrast medium leakage 24 cases, haemobilia 18 cases) and clinically registered complications in 11% (26/237 cases: bile or blood leakage with or without peritonitis in 10 cases). Two deaths occurred. When possible, a drainage catheter was inserted for decompression. This was performed on 184 occasions in 139 patients--failure rate was 5 per cent. Unsuccessful attempt to introduce a drainage catheter constituted a major complication risk occurring in 5/13 cases (38%). Signs of infection were frequent though these complications were not a major problem in this series. Various possibilities to reduce complications and infections are discussed.

Adenoma, Bile Duct↗
PubMed1983

Pharmacologic manipulation of lower esophageal sphincter pressure. A possible means of treatment of variceal bleeding.

Ten patients with portal hypertension and esophageal varices had percutaneous transheptic portography with selective catheterization of the short gastric or left gastric vein. The effect was studied on variceal blood flow after injection of various drugs (vasopressin IV, pentagastrin IV, somatostatin IV, domperidone IV, and methylcholine SC). Vasopressin had no effect on variceal flow; pentagastrin gave a total occlusion of flow in five of nine patients; somatostatin interrupted the flow in one of four patients; domperidone obstructed flow completely in one patient, while another receiving the same dose was unaffected; methylcholine did not affect the flow in three patients examined.

Adult↗
PubMed1983

Upper G-I bleeding following intraarterial chemotherapy infusion.

Two cases of severe upper G-I bleeding associated with hepatic 5-PU infusion are presented. This bleeding originated from duodenal ulcers caused by perforation of the gastroduodenal artery by the infusion catheter. They were visualized both at angiography which showed contrast leakage to the duodenum, and at gastroscopy, where the infusion catheter could be seen in the ulcer crater. The incidence and possible pathogenesis of peptic ulcer disease following hepatic infusion chemotherapy is discussed.

Arteries↗
PubMed1982

Angiographic and computed tomographic appearance of secondary carcinoid of the liver.

Liver angiograms of 27 patients with hepatic carcinoid metastases were analyzed for distribution, size, degree of vascularity, and patterns of tumor staining. Computed tomography (CT) scans were evaluated before and after bolus contrast administration in 13 of the cases. The diagnostic capability of the two procedures was compared. Angiography detected metastases, some less than 1 cm in size in all 13 patients; in 5 of 13 cases (38.5%) CT did not detect any hepatic metastases. In the eight patients in whom CT demonstrated metastases, the patterns of lesions and usefulness of contrast varied. Angiography is essential for evaluation of patients with suspected carcinoid metastases to the liver.

Angiography↗
PubMed1982

Evaluation of splenic embolization in patients with portal hypertension and hypersplenism.

Twenty-five patients with hypersplenism caused by portal hypertension were treated by repeated partial splenic embolization. Fourteen surviving patients were followed for up to six years showing a good response on peripheral blood count and bleeding tendency. Three patients died in connection with the treatment and another eight died within half a year because of the underlying liver disease. The discomfort and complications of fever, pain, pleural effusion, and abscess formation and the possibility to avoid these by repeated partial embolization under antibiotic cover are discussed. The results are compared with reports in the reviewed actual literature and the splenic embolization is given a place among the means of a successful selective symptomatic treatment of partial hypertension.

Adult↗
PubMed1982

Gelfoam powder embolization of the hepatic artery in liver metastases of carcinoid tumors.

Five patients with liver metastases of carcinoid tumors were treated with transcatheter embolization of the liver arteries with gelfoam powder. In three of four patients with flushing symptoms, these symptoms disappeared immediately after the treatment. One patient remained free of symptoms for 6 months. Another patient was free of symptoms at 1-month control but 1 year later he again had slight symptoms. The third patient had slight recurring symptoms at 1-month control. Liver angiograms performed on four patients 1 month after the embolization showed recanalized arteries and reduced vascularity of the tumors.

Aged↗
PubMed1981

[Experience with the percutaneous transhepatic insertion of a bile duct endoprosthesis (author's transl)].

In thirty patients with extrahepatic cholestasis because of a malignant tumor a permanent bile endoprosthesis was inserted nonsurgically. As prosthesis a teflon tube (OD/ID4.0/3.0mm) was used without side holes (13 cases) or with side holes (17 cases). The bile was drained through the endoprosthesis during a period of 1-32 weeks. The drainage function of the endoprosthesis without side holes was classified as partially effective in seven cases and as insufficient in six cases. The drainage function of the endoprosthesis with side holes was judged as optimal in four cases, partially effective in ten and insufficient in three cases. The dysfunction of the endoprosthesis in nine of thirty cases was caused by lack of side holes, spontaneous occlusion or spontaneous dislocation of the prosthesis. Eight patients developed symptoms of cholangitis. In four cases sepsis occurred after insertion of the prosthesis. One patient died from the sequelae of an intrahepatic pseudoaneurysm, which had developed from a damaged segmental artery following the transhepatic bile drainage.

Adult↗
PubMed1981

Personnel exposure to radiation at some angiographic procedures.

Personnel exposure to radiation was investigated during radiological procedures where x-ray shielding is particularly difficult. Ten percutaneous transhepatic cholangiographies, four percutaneous transhepatic portographies, and four coronary angiographies are included in the study. Exposure to radiation was measured at several anatomical sites for both the radiologist and the assisting nurse. Effective dose equivalents as proposed by the International Commission on Radiological Protection (ICRP) were estimated from the registered absorbed doses.

Angiography↗
PubMed1981

Angiography in pancreatic disease reevaluated. A prospective and blind evaluation.

Eighty-six consecutive pancreatic angiographies were reviewed prospectively. Ater more than one year 79 of them were "blindly" and independently reviewed by three radiologists. The results concerning accuracy, value three radiologists. The results concerning accuracy, value of superselective technique at malignancy and prediction of extirpability at malignancy were compared. The accuracy was similar, i.e. at malignancy 92 and 86 per cent (mean), respectively, as the prediction of extirpability 88 and 80 per cent (mean), respectively. The value of superselective technique differed considerably, 55 and 14 per cent (mean), respectively, and this is discussed. Pancreatic angiography in relation to CT, ultrasound and ERCP is discussed and considered to be of value late in the diagnostic program.

Aged↗
PubMed1981

Gastrointestinal bleeding caused by haemosuccus pancreaticus. A presentation of two cases.

Two cases of gastro-intestinal bleeding due to haemosuccus pancreaticus (hemorrhage through the pancreatic duct) are presented. Both patients had hematemesis and melena in combination with epigastric pain and hyperamylasemia. Angiography revealed aneurysms of the splenic artery as the probable source of bleeding. Central ligation of the splenic artery with splenectomy cured both patients. Angiographic obliteration of the splenic aneurysm was used preoperatively in one case.

Adult↗
PubMed1980

A large-bore teflon endoprosthesis with side holes for nonoperative decompression of the biliary tract in malignant obstructive jaundice.

A large-bore Teflon tube with side holes was used for nonsurgical palliative bile drainage in eight patients with malignant tumors. The drainage period ranged from 5 to 26 weeks. The bile drainage through the endoprosthesis was regarded as optimal in two patients, satisfactory in four, and ineffective in two. Significant complications of the method are intervening bile duct infections, risk of sepsis, spontaneous dislodgement, and occlusion of the endoprosthesis.

Adult↗