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Biomedical subjects

A Lunderquist

Publications and source records attributed to A Lunderquist.

At least 91 records · Page 5Linked to original sources
PubMed1978

Arterial changes during treatment with intrahepatic arterial infusion of 5-fluorouracil.

Changes in the liver arteries ranging from minimal irregularities in occlusions and development of aneurysms were investigated in 27 patients who received intra-arterial infusion of 5-FU in the hepatic artery. Variations in the arterial caliber peripheral to the hilum of the liver were noted in 13 of the patients. Further investigation of such arterial changes may be important in controlling the growth of liver metastases.

Adult↗
PubMed1978

Therapeutic applications of catheter cholangiography.

Percutaneous transhepatic catheterization of the biliary tree was performed in 23 patients. In 21 the catheter was advanced past an obstructing lesion into the distal common bile duct and duodenum to establish antegrade biliary drainage. The catheter was left permanently in place as a form of endoprosthesis in 5 patients.

Adult↗
PubMed1978

Selective phlebography in carcinoma of the pancreas.

Eighteen patients with obstructive jaundice were examined by pancreatic phlebography. In 15 cases the final diagnosis was carcinoma of the pancreas, in 3 cholangiocarcinoma. The normal phlebographic anatomy and the morphologic abnormalities in patients with carcinoma of the pancreas are described. The accuracy of pancreatic phlebography in the diagnosis of carcinoma of the pancreas and cholangiocarcinoma is evaluated.

Aged↗
PubMed1978

Percutaneous transhepatic portography.

The technique, indications, contraindications and complications of percutaneous transhepatic portography and selective catheterization of the major and minor veins draining the splanchnic organs based on the experience of 200 cases are described. The advantage of this method is discussed and compared with transjugular and transumbilical portography.

Adult↗
PubMed1978

Isobutyl 2-cyanoacrylate (bucrylate) in obliteration of gastric coronary vein and esophageal varices.

Percutaneous transhepatic portography was performed in 22 patients with liver cirrhosis and portal hypertension. All patients had bled or were bleeding from presumed esophageal varices. One or more veins feeding esophageal varices were occluded with bucrylate. Follow-up examination in eight patients 1-12 months later showed recanalization of previously obliterated veins in six; however, these veins were markedly smaller than before the procedure. In patients where veins were still occluded, new veins had opened up and carried blood to the esophageal varices, which were filled to a lesser degree than before. In our experience, bucrylate is superior to Gelfoam, thrombin, and Etolein in producing venous occlusion.

Adult↗
PubMed1978

Complications of angiographic examinations.

A prospective study of angiographic complications in 1,217 consecutive adult patients seen during a 1 year period was undertaken. Neuroangiographic and angiocardiographic examinations were excluded. All forms of complications were reported, including those occurring within 3 days after the examination, and the degree of seriousness was evaluated. Complications at puncture which required surgery occurred in 0.14%. Potentially serious complications from catheter manipulation for selective position in abdominal arteries occurred in 0.5%. At catheterization of the internal iliac artery there was a high frequency of lesions (14.3%), one an indirect cause of lethal outcome. Nine patients had thromboembolic complications, and the value of heparinized catheters is discussed. The frequency of serious complications due to contrast agent was remarkably low.

Abdomen↗
PubMed1978

Localization of insulinomas and islet cell hyperplasias by pancreatic vein catheterization and insulin assay.

Percutaneous transhepatic portal vein catheterization and transfemoral portal and caval catheterizations were performed under local anesthesia in five patients with symptoms of organic hypoglycemia. During the investigation, results of pancreatic phlebography revealed the pancreatic venous anatomy. Blood obtained from the celiac artery, caval branches and pancreatic veins was assayed for insulin by two different radioimmunoassay methods. Pathologically high, pancreatic arteriovenous insulin differences in two patients with insulinomas and in two patients with islet cell hyperplasia. In one of the patients with an insulinoma, one of the assays failed to detect the tumor insulin. This inconsistency still remains unexplained. Angiography revealed a pancreatic abnormality in only two patients. During operation, two of the tumors were found upon palpation and inspection. Pancreatic resections were performed according to the findings of pathologic hormone differences in all five patients. Immunocytochemistry revealed that three of the patients had insulin-producing tumors and two had local islet cell hyperplasia. Catheterizations performed two months postoperatively confirmed the radicality of the operation in all patients, with the possible exception of one patient. In one patient, a recurrance was detected by catheterization ten months postoperatively.

Adenoma, Islet Cell↗
PubMed1978

Correlation between percutaneous transhepatic portography and clinical findings in 56 patients with portal hypertension.

56 consecutive patients with portal hypertension were studied with percutaneous transhepatic portography and the results were correlated to clinical findings and the number of upper gastrointestinal haemorrhages and the size of the individual bleeding. An abundance of collateral paths was noted in most patients. No regularity in development of these collaterals was found. It was not correlated to liver disease etiology, sex or liver function parameters. Portal pressure was not correlated to the size or amount of collaterals. In four patients with liver cirrhosis hepato-fugal flow in one segment of the liver was noted proving that portal flow through the liver is not uniform in this disease. The size of the haemorrhages was only correlated to presence of hepato-fugal flow in the main stem of the portal vein. It was not correlated to the estimated size of the oesophageal varices or to portal pressure. Percutaneous transhepatic portography seems to be of little help in selecting "high risk bleeders" in portal hypertension. Other factors may be of greater help in this task as indicated by the findings in this investigation that patients with alcohol cirrhosis had larger haemorrhages than those with cirrhosis of another etiology and that patients with none or few bleeding episodes had higher thrombocyte count than those with several haemorrhages.

Aged↗
PubMed1977

Islet cell hyperplasia localized by pancreatic vein catheterization and insulin radioimmunoassay.

A patient with organic hypoglycemia but with normal pancreatic arteriography was investigated with pancreatic vein catheterization for insulin immunoassay. Very high insulin concentrations (1, 130 micronU/ml) were found in a vein draining part of the pancreatic tail. Even though no tumor was found at operation, distal hemipancreatectomy was performed according to the assay findings. Histology and immunohistochemistry revealed a localized islet hyperplasia.

Adult↗
PubMed1977

Follow-up of patients with portal hypertension and esophageal varices treated with percutaneous obliteration of gastric coronary vein.

Percutaneous transhepatic catheterization of the portal vein was performed in 21 patients with liver cirrhosis and esophageal varices. Coronary and short gastric veins were selectively catheterized and obliterated. The examination was performed to stop bleeding in 6 patients and was successful in 5. Follow-up examination showed recanalization of previously obliterated veins in 13 of 16 patients.

Adult↗
PubMed1977

The angiographic appearance of thymic tumors.

Angiography of the internal mammary artery was performed in 30 patients with suspected tumors in the anterior mediastinum. In 3 patients, thymic venography was also performed. In 13 lymphoepithelial thymomas, a smooth outline with the arteries penetrating the periphery of the tumor was demonstrated. Frequently, neovascularity but never encasement of large arteries or arteriovenous (AV) shunting was exhibited. In the lymphoepithelial thymomas of the cell-rich type, the accumulation of contrast medium and neovascularity were pronounced. This type of thymoma may possibly be locally more invasive than others. In carcinomas, the arteries penetrated the tumor and AV shunting was common. Arteriography was superior to venography in the few patients in whom both examinations were performed. Angiographically, it should be possible to differentiate thymomas from carcinomas.

Adult↗
PubMed1977

Subintimal injection of contrast medium as a complication of selective abdominal angiography.

The frequency, cause and sequelae of subintimal injection of contrast medium as a complication of selective abdominal angiography have been evaluated. The frequency increased considerably with the degree of superselectivity. The risk of total occlusion and clot formation in the renal artery after subintimal injection is high. Injury and total occlusion of the celiac and hepatic arteries have better chance for healing than of the renal arteries. A subintimal injection in the proximal part of the superior mesenteric artery may result in the development of an aneurysm.

Abdomen↗
PubMed1977

Tumor vessels. Angiographic-histopathologic correlation.

The operative or autopsy specimens of 20 cases of renal carcinoma, 10 cases of pancreatic carcinoma and 10 cases of malignant glioma were studied histopathologically and compared with the in vivo angiographic findings. The study was focused on the presence or not of newly formed tumor vessels trying to eludicate if the abnormal vessels seen on angiography are newly formed tumor vessels or altered preexisting vessels.

Adenocarcinoma↗