An exogenous free radical generating system added to isolated brain capillaries induces degradation of phospholipids. This inductive effect reflects increased phospholipase activities as measured by fatty acid composition of various phospholipid fractions. The correlation of phospholipid degradation with stimulation of phospholipases was further investigated by using cationic amphiphilic agents, which are known to be phospholipase A2 inhibitors. The breakdown of phospholipids was inhibited by the pretreatment of isolated capillaries with these drugs.

Animals↗

PubMed1980

Investigation of a novel liver alcohol dehydrogenase catalyzed redox-elimination reaction involving arylnitroso substrate analogues.

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Alcohol Oxidoreductases↗

PubMed1979

An immunocytotoxicity assay for neural cells in monolayer cultures.

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Animals↗

PubMed1979

Neural cell sequestration on immunoaffinity columns.

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Animals↗

PubMed1977

Reaction of the basic trypsin inhibitor from bovine pancreas with the chelator-activated 7S nerve growth factor esteropeptidase.

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Animals↗